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Merck

A-923

Amitriptyline hydrochloride solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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A propos de cet article

Formule empirique (notation de Hill) :
C20H24ClN
Numéro CAS:
549-18-8
Poids moléculaire :
313.86
UNSPSC Code:
41116107
MDL number:
MFCD00012537
NACRES:
NA.24
EC Number:
200-659-6

Principaux documents

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InChI key

KFYRPLNVJVHZGT-UHFFFAOYSA-N

InChI

1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H

SMILES string

Cl.CN(C)CC\C=C1\c2ccccc2CCc3ccccc13

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

300

Gene Information

human ... SLC6A2(6530), SLC6A4(6532)

Catégories apparentées

General description

A Certified Spiking Solution® suitable for use in LC/MS or GC/MS applications in clinical toxicology, forensic analysis, urine drug testing, prescription monitoring or pharmaceutical research. Amitriptyline, marketed as the brand drug Elavil, Tryptizol, or Laroxyl, is a tricyclic antidepressant used in the treatment of major depression, clinical/endogenous depression and involutional melancholia.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Classe de stockage

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificats d'analyse (COA)

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Recreational amitriptyline toxicity mimicking basilar artery stroke.
Jonathan Birns et al.
European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 20(2), 139-140 (2013-02-26)
Christian Janfelt et al.
Journal of mass spectrometry : JMS, 48(3), 361-366 (2013-03-16)
Displaced dual-mode imaging (DDI) is introduced as a method for simultaneous imaging in positive and negative-ion mode on the same sample with desorption electrospray ionization imaging, as well as a method for simultaneous imaging in full-scan and tandem mass spectrometry
P U Nwosu
Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria, 21(2), 252-255 (2013-01-15)
Ekboms syndrome is an uncommon, chronic disorder that often has a familial basis, with evidence of autosomal dominant inheritance. It occurs in about 5% of adults and about one third of patients would have multiple affected family members. This report
Daniel J Stein et al.
The Annals of otology, rhinology, and laryngology, 122(1), 20-24 (2013-03-12)
We evaluated the safety and efficacy of amitriptyline hydrochloride in treating idiopathic chronic laryngeal irritability. A retrospective chart review identified patients treated with amitriptyline for laryngeal irritability in an academic otolaryngology practice. Subjects who had documented medication compliance and a
David Temesi et al.
Journal of pharmaceutical and biomedical analysis, 76, 164-168 (2013-01-22)
Procedures for drug monitoring based on Dried Blood Spot (DBS) sampling are gaining acceptance for an increasing number of clinical and preclinical applications, where ease of use, small sample requirement, and improved sample stability have been shown to offer advantages
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