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Merck

D-015

Diphenhydramine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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A propos de cet article

Formule empirique (notation de Hill) :
C17H22ClNO
Numéro CAS:
147-24-0
Poids moléculaire :
291.82
NACRES:
NA.24
PubChem Substance ID:
329798588
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00012479

Principaux documents

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InChI key

PCHPORCSPXIHLZ-UHFFFAOYSA-N

InChI

1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

SMILES string

CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

Quality Level

300

Gene Information

human ... HRH1(3269)

Catégories apparentées

General description

Diphenhydramine is an antihistamine sold over the counter under the trade name Benadryl® and in other over the counter medications such as Tylenol PM, Advil PM, and Excedrin PM. Dihydramine is also consumed recreationally as a euphoriant and a deliriant.

Legal Information

Benadryl is a registered trademark of Johnson & Johnson
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Classe de stockage

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificats d'analyse (COA)

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Marc Marino et al.
Journal of neuroscience methods, 211(1), 1-10 (2012-09-14)
Pruritus, the sensation of itch, which evokes reflex scratching behavior, has a diverse etiology. Because of its clinical significance, mechanisms of pruriception are an important topic. In the present work we describe and validate a paw motion detector (PMD) system.
Eugene W Schwilke et al.
Journal of forensic sciences, 51(5), 1191-1198 (2006-10-05)
We have previously reported on patterns of drug and alcohol use in fatally injured drivers in Washington State. Here we revisit that population to examine how drug use patterns have changed in the intervening 9 years. Blood and serum specimens
A D Rollstin et al.
Clinical toxicology (Philadelphia, Pa.), 51(1), 50-53 (2012-12-01)
There are few reports of acetaminophen overdose in hypothermic patients and even fewer reports describing profound hypothermia. The kinetics, risk of hepatotoxicity, and the possible dose adjustments to N-acetylcysteine (NAC) therapy are not known in this setting. A 37-year-old female
Edward Topp et al.
The Science of the total environment, 439, 136-140 (2012-10-16)
The widely used antihistamine diphenhydramine is present in municipal biosolids, and is detected in runoff from agricultural land fertilized with biosolids. In the present study the kinetics and major pathways of diphenhydramine dissipation in a loam, sandy loam, and clay
Paige M Evans et al.
American journal of veterinary research, 73(12), 1983-1986 (2012-11-28)
To evaluate the effects of oral administration of diphenhydramine on pupil diameter, intraocular pressure (IOP), tear production, tear film quality, corneal sensitivity, and conjunctival goblet cell density (GCD) in clinically normal adult dogs. 12 healthy adult dogs. All dogs received
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