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Merck

M-005

Morphine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill) :
C17H19NO3
Numéro CAS:
57-27-2
Poids moléculaire :
285.34
NACRES:
NA.24
UNSPSC Code:
41116107

Nom du produit

Morphine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

InChI

1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1

InChI key

BQJCRHHNABKAKU-KBQPJGBKSA-N

SMILES string

CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal); Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet
kontrollierte Droge in Deutschland

Quality Level

300

Gene Information

human ... OPRM1(4988)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

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Catégories apparentées

Application

The certified reference solution (CRM) in solution can also be used as follows:
  • Development of a hydrogel-modified carbon paste electrode (HCPE) for the electrochemical determination of morphine in very low volume solutions using differential pulse voltammetry
  • Combination of magnetic molecularly imprinted solid phase extraction (MMISPE) with high-performance liquid chromatography (HPLC) to analyze urine samples for quantifying morphine
  • Electrochemical detection and measurement of morphine and 3,4-methylenedioxymethamphetamine (MDMA) in human urine and serum samples using carbon nanohorns modified with Pt nanoparticles (CNHs@PtNPs) based sensor
  • Simultaneous determination of morphine and naltrexone in bulk and their combined solid dosage formulations using a stability-indicating high-performance liquid chromatographic method combined with a photodiode array detector
  • Colorimetric estimation of morphine and ibuprofen in human serum and urine samples as per the difference in the aggregation of citrate-capped gold nanoparticles (AuNPs) analyzed by infra-red (IR) spectroscopy and transmission electron microscopy (TEM)

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

General description

This certified analytical reference standard is suitable for a variety of GC/MS or LC/MS applications from pain prescription monitoring, clinical toxicology, and urine drug testing to pharmaceutical research and forensic analysis.

Morphine is a natural phenolic alkaloid, commonly used as an analgesic and anti-inflammatory properties. Sold under trade names including MS Contin®, Kadian®, Oramorph®, and Roxanol, morphine is also a commonly abused recreational drug due to its widespread availability and a high potential for addiction.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Kadian is a registered trademark of Actavis Elizabeth LLC
MS Contin is a registered trademark of Purdue Frederick Company
Oramorph is a registered trademark of AAIPharma, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Classe de stockage

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

In response.
Alain Gorgeat
Anesthesia and analgesia, 116(6), 1391-1391 (2013-07-12)
Thitima Chinachoti et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96(5), 589-594 (2013-06-12)
Presently, in Siriraj Hospital, intrathecal morphine is routinely used in spinal anesthesia for postoperative pain control in more than 600 cases per month with doses lower than 0.3 mg. However, the incidence of side effects is high. This retrospective data
A Bilir
Clinical and experimental obstetrics & gynecology, 40(1), 118-121 (2013-06-04)
Pain management has a particular importance after Cesarean section. This study was undertaken in order to document the efficacy and side-effects of epidural morphine instead of patient-controlled analgesia technique used for the control of post-cesarean pain during postoperative 24-48 hours.
Importance of reducing pain during routine procedures.
Michael C Petty
Journal of the American Veterinary Medical Association, 242(8), 1048-1048 (2013-05-15)
Beatrice Setnik et al.
Journal of opioid management, 9(2), 139-150 (2013-05-28)
To evaluate whether intact or crushed doses of an extended-release formulation of morphine sulfate surrounding an inner core of sequestered naltrexone (MSN) induces signs and symptoms of withdrawal in opioid-dependent patients. Randomized, double-blind, two-way crossover study. Single center. Fourteen patients
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