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Merck

07-383

Anti-Akt3/PKBγ Antibody

Upstate®, from rabbit

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunoprecipitation (IP)
western blot
Species reactivity:
human
Citations:
15
Technique(s):
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
Q9Y243

Principaux documents

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Nom du produit

Anti-Akt3/PKBγ Antibody, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_005465

UniProt accession no.

Q9Y243

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... AKT3(10000)

Analysis Note

Control
IGF-I stimulated HEK293 cell lysates
routinely evaluated by immunoprecipitating active Akt3/PKBγ from IGF-I stimulated HEK293 cell lysates.

Application

Anti-Akt3/PKBγ Antibody is an antibody against Akt3/PKBγ for use in IP & WB.

Biochem/physiol Actions

Recognizes Akt3/PKBγ.

General description

~60 kDa

Immunogen

peptide corresponding to amino acids 119-131 of human Akt3/PKBgamma

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: AB3136

Physical form

Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

Certificats d'analyse (COA)

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Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions
Katome, T., et al
The Journal of Biological Chemistry, 278, 28312-28323 (2003)
Demetris C Iacovides et al.
Molecular & cellular proteomics : MCP, 12(11), 3210-3220 (2013-08-10)
Breast cancer subtype-specific molecular variations can dramatically affect patient responses to existing therapies. It is thought that differentially phosphorylated protein isoforms might be a useful prognostic biomarker of drug response in the clinic. However, the accurate detection and quantitative analysis
Anna Joy et al.
Journal of neuro-oncology, 130(1), 43-52 (2016-10-21)
The growth factor receptor/PI3K/AKT pathway is an important drug target in many cancers including Glioblastoma. AKT, a key node in the pathway, has 3 isoforms, AKT1, AKT2 and AKT3. Here we investigate their role in GBM. We find each activated
Conrad P Hodgkinson et al.
Biochemistry, 41(32), 10351-10359 (2002-08-07)
Protein kinase B (PKB), also known as Akt, is a serine/threonine protein kinase controlled by insulin, various growth factors, and phosphatidylinositol 3-kinase. Full activation of the PKB enzyme requires phosphorylation of a threonine in the activation loop and a serine
François Fabi et al.
PloS one, 12(5), e0177387-e0177387 (2017-05-06)
Infertility is constantly increasing in Canada, where 16% of Canadian couples are experiencing difficulty conceiving. It is thought that infertility can emanate from the dysregulated communication between the embryo and the maternal endometrium. In order to allow for this window
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Numéro d'article de commerce international

RéférenceGTIN
07-38304053252323072

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