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Merck

07-540

Anti-acetyl-Histone H3 (Lys36) Antibody

serum, Upstate®

Synonyme(s) :

H3K36Ac, Histone H3 (acetyl K36)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Nom du produit

Anti-acetyl-Histone H3 (Lys36) Antibody, serum, Upstate®

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

multiplexing: suitable
western blot: suitable

NCBI accession no.

NP_003484

UniProt accession no.

Q16695

shipped in

wet ice

target post-translational modification

acetylation (Lys36)

Quality Level

100

Gene Information

human ... H3F3B(3021)

Analysis Note

Routinely evaluated by immunoblot.

Application

Suggested dilutions:
Western Blot: 1:5000 - 1:20,000

ChIP Analysis: A representative lot was used by an independent laboratory for ChIP (Gatta, R., et al. (2011). Epigenetics. 6(4):526-534.)
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
Use Anti-acetyl-Histone H3 (Lys36) Antibody (Rabbit Polyclonal Antibody) validated in WB, Mplex to detect acetyl-Histone H3 (Lys36) also known as H3K36Ac, Histone H3 (acetyl K36).

Biochem/physiol Actions

Broad species cross reactivity is expected
Recognizes Histone H3 when acetylated on Lys36

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

~17kDa

Immunogen

KLH-conjugated, synthetic peptide containing the sequence ...GV[AcK]KP... in which [AcK] corresponds to acetyl-lysine 36 of human histone H3.

Physical form

100μl of rabbit antiserum containing 0.05% sodium azide and 30% glycerol.
Antiserum

Preparation Note

2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Cluster analysis reveals differential transcript profiles associated with resistance training-induced human skeletal muscle hypertrophy.
Thalacker-Mercer, A; Stec, M; Cui, X; Cross, J; Windham, S; Bamman, M
Physiological Genomics null
Anton Eberharter et al.
EMBO reports, 3(3), 224-229 (2002-03-08)
The organization of eukaryotic chromatin has a major impact on all nuclear processes involving DNA substrates. Gene expression is affected by the positioning of individual nucleosomes relative to regulatory sequence elements, by the folding of the nucleosomal fiber into higher-order
Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.
Thapa, A; Morris, L; Xu, J; Ma, H; Michalakis, S; Biel, M; Ding, XQ
The Journal of Biological Chemistry null
Raffaella Gatta et al.
Epigenetics, 6(4), 526-534 (2011-02-10)
Histones post-translational modifications (PTMs) are crucial for transcriptional control, defining positive and negative chromatin territories. We previously described an extensive methylation-acetylation switch on cell cycle promoters using a single nucleosome ChIP assay. A key issue is how PTMs are locally
Valerie Migeot et al.
Methods in molecular biology (Clifton, N.J.), 1721, 25-34 (2018-02-10)
The distribution of modified histones within the fission yeast Schizosaccharomyces pombe genome is ultimately dependent upon the transcriptional activity and in turn influences the ability of the polymerases to bind and progress through the chromatin template. The Chromatin Immunoprecipitation-Polymerase Chain
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Numéro d'article de commerce international

RéférenceGTIN
07-54004053252269998

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