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Merck

07-594

Anti-Histone H2A.Z Antibody

serum, Upstate®

Synonyme(s) :

Anti-H2A.Z-1, Anti-H2A.z, Anti-H2A/z, Anti-H2AFZ, Anti-H2AZ

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
28

Principaux documents

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biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

packaging

antibody small pack of 25 μL

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

UniProt accession no.

P0C0S5

shipped in

ambient

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... H2AFZ(3015)

General description

16kDa

Immunogen

peptide containing the sequence SLIGKKGQQ, corres-ponding to the C-terminus of human histone H2A.Z

Application

Detect Histone H2A.Z also known as H2AZ histone with Anti-Histone H2A.Z Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Biochem/physiol Actions

Broad species cross-reactivity is expected
C-terminus of histone H2A.Z

Physical form

Serum
0.05% sodium azide before the addition of glycerol to 30%

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on acid extracted proteins from HeLa cells and recombinant Histone H2A.Z (Catalog #14-597), no cross-reactivity with Histone H2A

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Zenab F Mchaourab et al.
Scientific data, 5, 180030-180030 (2018-03-07)
The human K562 chronic myeloid leukemia cell line has long served as an experimental paradigm for functional genomic studies. To systematically and functionally annotate the human genome, the ENCODE consortium generated hundreds of functional genomic data sets, such as chromatin
H2A.Z overexpression promotes cellular proliferation of breast cancer cells.
Amy Svotelis,Nicolas Gevry,Gilles Grondin,Luc Gaudreau
Cell Cycle null
Molecular cloaking of H2A.Z on mortal DNA chromosomes during nonrandom segregation.
Yang Hoon Huh,James L Sherley
Stem Cells null
Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes.
Ontoso, D; Kauppi, L; Keeney, S; San-Segundo, PA
Chromosoma null
Chunyuan Jin et al.
Nature genetics, 41(8), 941-945 (2009-07-28)
To understand how chromatin structure is organized by different histone variants, we have measured the genome-wide distribution of nucleosome core particles (NCPs) containing the histone variants H3.3 and H2A.Z in human cells. We find that a special class of NCPs
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Numéro d'article de commerce international

RéférenceGTIN
07-59404053252405662
07-594-25UL04054839337772

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