5.06129
α-(Methylamino)isobutyric Acid
Synonyme(s) :
α-(Methylamino)isobutyric Acid, Neutral Amino Acid Transporter A inhibitor, MeBIA
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A propos de cet article
assay
≥98% (TLC)
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 100 mM
storage temp.
−20°C
SMILES string
[N+H2](C(C)(C)C(=O)[O-])C
InChI
1S/C5H11NO2/c1-5(2,6-3)4(7)8/h6H,1-3H3,(H,7,8)
InChI key
DLAMVQGYEVKIRE-UHFFFAOYSA-N
General description
Biochem/physiol Actions
Glutamine transporter
Packaging
Preparation Note
Other Notes
Lee, Y., et al., 2013. J. Psych. & Neurosci.: JPN.38, 183.
Blot, A., et al. 2009. Neurosci.164, 998.
Legal Information
Disclaimer
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Contenu apparenté
"Apoptosis & Autophagy in Cancer: Cell Survival by Eluding Cell Death The ability of tumor cells to elude programmed cell death, also known as apoptosis, is a hallmark of most types of cancer. Similary, autophagy is a highly regulated, homeostatic degradative process where cells destroy their own components via the lysosomal machinery and recycle them for prolonged cell survival. Via extensive crosstalk with pro-apoptotic signaling pathways, autophagy can also contribute to cell death and greatly influence general cell health. Elucidating the correlation between autophagy and apoptotic cell death has become the focus of a great deal of research, particularly in tumor biology. On one hand, autophagy may induce cell death by degrading essential components; on the other hand, it may facilitate survival of cancer cells under unfavorable metabolic conditions."