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Merck

535140

Protease Inhibitor Cocktail III

Animal-Free, liquid, for the inhibition of aspartic, cysteine, serine proteases and aminopeptidases

Synonyme(s) :

Animal free Protease inhibitor

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A propos de cet article

UNSPSC Code:
12352200
NACRES:
NA.54
Form:
liquid
Solubility:
water: soluble
Storage temp.:
−20°C

Principaux documents

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Nom du produit

Protease Inhibitor Cocktail Set III, Animal-Free, Protease Inhibitor Cocktail Set III, Animal-Free, is a cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine & serine proteases & aminopeptidases.

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

solubility

water: soluble

shipped in

wet ice

storage temp.

−20°C

Catégories apparentées

Biochem/physiol Actions

Cell permeable: no
Primary Target
Aspartic, cysteine, and serine proteases as well as aminopeptidases
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Irritant (B)

General description

A cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine, and serine proteases as well as aminopeptidases. This cocktail is recommended for use with mammalian cell and tissue extracts. Each vial contains 100 mM AEBSF, HCl (Cat. No. 101500), 80 µM Aprotinin (Cat. No. 616371), 5 mM Bestatin (Cat. No. 200484), 1.5 mM E-64 (Cat. No. 324890), 2 mM Leupeptin Hemisulfate (Cat. No. 108975) and 1 mM Pepstatin A (Cat. No. 516482). Available as 1 ml vial or a set of 5 x 1 ml.

Physical form

In 1 ml DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Classe de stockage

10 - Combustible liquids

wgk

WGK 2

flash_point_f

188.6 °F

flash_point_c

87 °C

Certificats d'analyse (COA)

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Ching-Hsin Huang et al.
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Mono- or dual-checkpoint inhibitors for immunotherapy have changed the paradigm of cancer care; however, only a minority of patients responds to such treatment. Combining small molecule immuno-stimulators can improve treatment efficacy, but they are restricted by poor pharmacokinetics. In this
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Despite the worldwide effect of the coronavirus disease 2019 (COVID-19) pandemic, the underlying mechanisms of fatal viral pneumonia remain elusive. Here, we show that critical COVID-19 is associated with enhanced eosinophil-mediated inflammation when compared to non-critical cases. In addition, we
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