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Merck

AB1570

Anti-GABA Transporter-1 Antibody, CT (a.a. 588-599)

Chemicon®, from rabbit

Synonyme(s) :

GAT-1

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
Species reactivity:
monkey, feline, rat, human, mouse, rabbit
Citations:
33
Technique(s):
immunohistochemistry: suitable
Uniprot accession no.:
P30531

Principaux documents

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Nom du produit

Anti-GABA Transporter-1 Antibody, CT (a.a. 588-599), Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

monkey, feline, rat, human, mouse, rabbit

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

suitability

not suitable for Western blot

NCBI accession no.

NM_003042.2

UniProt accession no.

P30531

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SLC6A1(6529)

Application

Anti-GABA Transporter-1 Antibody, C-terminus (a.a. 588-599) is an antibody against GABA Transporter-1 for use in IH.
Immunohistochemistry: 1:500-1:750 on 4% paraformaldehyde fixed or 4% paraformaldehyde and 0.2% glutaraldehyde fixed tissue. It is recommended that the antibody be diluted in PBS containing 10% normal goat serum and 0.5% Triton X-100. AB1570 has been used for both light and electron microscopic studies of rat retina, cortex and hippocampus.

Note: AB1570 is not recommended for Western blot use. See AB1570W.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

GABA Transporter-1 (GAT-1), C-terminus. No cross-reactivity to the C-termini of other transmitter transporters detected.

Immunogen

Epitope: C-terminus (a.a. 588-599)
Rat GAT-1, C-terminus (aa 588-599)

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified antibody. Lyophilized from in 0.1 M PBS with 1% BSA and 0.1% sodium azide. Reconstitute with 100 μL of sterile distilled water.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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GHS07

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Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Constantino Sotelo
The Journal of comparative neurology, 506(2), 240-262 (2007-11-21)
The acquisition of the dynamic balance between excitation and inhibition in developing Purkinje cells, necessary for their proper function, is analyzed. Newborn (P0) mouse cerebellum contains glutamatergic (VGLUT2-IR) and gamma-aminobutyric acid (GABA)-ergic (VIAAT-IR) axons. The former prevail and belong to
Lu Pu et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 818451-818451 (2013-02-01)
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation. Here we investigated regulation of GABA transporter GAT1 by δOR in rats and in
Elena E Bagley et al.
Neuron, 45(3), 433-445 (2005-02-08)
Adaptations in neurons of the midbrain periaqueductal gray (PAG) induced by chronic morphine treatment mediate expression of many signs of opioid withdrawal. The abnormally elevated action potential rate of opioid-sensitive PAG neurons is a likely cellular mechanism for withdrawal expression.
Xinjun Wang et al.
The Journal of physiology, 592(19), 4257-4276 (2014-08-03)
GABAergic terminals of chandelier cells exclusively innervate the axon initial segment (AIS) of excitatory neurons. Although the anatomy of these synapses has been well-studied in several brain areas, relatively little is known about their physiological properties. Using vesicular γ-aminobutyric acid
Pericellular innervation of neurons expressing abnormally hyperphosphorylated tau in the hippocampal formation of Alzheimer's disease patients.
Blazquez-Llorca, L; Garcia-Marin, V; Defelipe, J
Frontiers in Neuroanatomy null
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Numéro d'article de commerce international

RéférenceGTIN
AB157004053252334696

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