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Merck

AB15766

Anti-Sox1 Antibody

Chemicon®, from rabbit

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
18
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse, rodent, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... SOX1(6656)

Immunogen

Synthetic peptide from human Sox1.

Application

Anti-Sox1 Antibody detects level of Sox1 & has been published & validated for use in WB, IH.
Research Sub Category
Neuronal & Glial Markers

Developmental Neuroscience
Western blot: 1:200-1:1,000 using ECL. Immunohistochemistry: 1:200-1:1,000. Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Reactivity with other species has not been confirmed.
Recognizes Sox-1, a high mobility group (HMG) transcription factor.

Physical form

Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Format: Purified

Other Notes

Replaces: AB5768

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Catarina M Seabra et al.
Molecular autism, 11(1), 45-45 (2020-06-07)
MBD5, encoding the methyl-CpG-binding domain 5 protein, has been proposed as a necessary and sufficient driver of the 2q23.1 microdeletion syndrome. De novo missense and protein-truncating variants from exome sequencing studies have directly implicated MBD5 in the etiology of autism
Cells with intense EGFR staining and a high nuclear to cytoplasmic ratio are specific for infiltrative glioma: a useful marker in neuropathological practice.
Burel-Vandenbos, F; Turchi, L; Benchetrit, M; Fontas, E; Pedeutour, Z; Rigau, V; Almairac et al.
Neuro-Oncology null
Jing Liu et al.
Stem cell reviews and reports, 8(4), 1129-1137 (2012-10-12)
microRNAs (miRNAs) are important modulators in regulating gene expression at the post-transcriptional level and are therefore emerging as strong mediators in neural fate determination. Here, by use of the model of human embryonic stem cell (hESC)-derived neurogenesis, miRNAs involved in
E Tian et al.
Cell reports, 16(3), 781-792 (2016-07-12)
Growing evidence indicates important roles for astrocytes in neurodevelopment and diseases. However, astrocytes and their roles in these processes remain poorly understood. Despite recent progress in reprogramming somatic cells into different types of neural cells, reprogramming to astrocytes has lagged.
Manasa P Srikanth et al.
Stem cells translational medicine, 10(7), 1081-1094 (2021-03-04)
Gaucher disease (GD) is a lysosomal storage disorder caused by mutations in GBA1, the gene that encodes lysosomal β-glucocerebrosidase (GCase). Mild mutations in GBA1 cause type 1 non-neuronopathic GD, whereas severe mutations cause types 2 and 3 neuronopathic GD (nGD). GCase deficiency

Numéro d'article de commerce international

RéférenceGTIN
AB1576604053252506482

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