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Merck

AB1954

Anti-Fibronectin Antibody

CHEMICON®, rabbit polyclonal

Synonyme(s) :

Cold-insoluble globulin, fibronectin 1, migration stimulating factor, migration-stimulating factor

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A propos de cet article

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
mouse, rat
Application:
ELISA, WB
Citations:
27
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Nom du produit

Anti-Fibronectin Antibody, Chemicon®, from rabbit

Quality Level

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

packaging

antibody small pack of 25 μL

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, western blot: suitable

UniProt accession no.

shipped in

ambient

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... FN1(2335)
mouse ... Fn1(14268)

General description

262 kDa
Fibronectin (FN) is involved in many cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/adhesion. Fibronectin exists in two main forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the ECM (extracellular matrix), and; 2) as a soluble disulphide linked dimer found in the plasma (plasma FN). The plasma form is synthesized by hepatocytes, and the ECM form is made by fibroblasts, chondrocytes, endothelial cells, macrophages, as well as certain epithelial cells.

Immunogen

Purified rat plasma fibronectin.

Application

Research Sub Category
ECM Proteins
Anti-Fibronectin Antibody detects level of Fibronectin & has been published & validated for use in ELISA & WB.
Research Category
Cell Structure

Biochem/physiol Actions

Other species have not been tested.
The antibody reacts with the 262 kDa fibronectin protein.

Physical form

Antigen Affinity Purified
Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Western Blot: Normal rat serum
Routinely evaluated by Western Blot on normal rat serum.

Western Blot Analysis:
0.05 μg/mL - 1 μg/mL antibody detected fibronectin in 15 μL of normal rat serum.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents



Ina V Martin et al.
American journal of physiology. Renal physiology, 314(1), F35-F46 (2017-09-15)
Complement factor C5a has two known receptors, C5aR, which mediates proinflammatory effects, and C5L2, a potential C5a decoy receptor. We previously identified C5a/C5aR signaling as a potent profibrotic pathway in the kidney. Here we tested for the first time the
Cláudia Silva Souza et al.
Experimental biology and medicine (Maywood, N.J.), 244(9), 758-769 (2019-05-02)
To date, no studies have been found evaluating the effects of physical exercise on renal function and structure changes in ovariectomized rats with type 1 diabetes. Therefore, this work emerges with an important tool for strengthening and expanding innovative research
Rugmani Padmanabhan Iyer et al.
American journal of physiology. Heart and circulatory physiology, 311(3), H822-H836 (2016-08-16)
The purpose of this study was to evaluate the effect of sham surgery in a minimally invasive surgical model of permanent coronary artery occlusion used to generate myocardial infarction (MI) in mice. Adult male C57BL/6J mice (3-6 mo old) were



Numéro d'article de commerce international

RéférenceGTIN
AB195404053252325403
AB1954-25UL04054839350481