AB4350
Anti-PRDM14 Antibody
from rabbit, purified by affinity chromatography
Synonyme(s) :
PR domain zinc finger protein 14, PR domain-containing protein 14
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A propos de cet article
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
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rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse, human
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PRDM14(63978)
General description
PR domain proteins (PRDMs) have been associated with many types of human cancers. PRDM14 was found to be up-regulated in breast cancer cells. The expression of PRDM14 to breast cancer cells actually increased cell proliferation and decreased the effect of chemotherapeutic drugs, while down-regulation of PRDM14 did the opposite. In addition to breast cancer, PRDM14 has recently been linked to non-small cell lung cancer development. PRDM14 also seems to play a role in the preservation of the self-renewal of human embryonic stem cells and transcriptional regulation.
~62 kDa observed
Immunogen
GST-tagged recombinant protein corresponding to the N-terminus of human PRDM14.
Application
This Anti-PRDM14 Antibody is validated for use in WB for the detection of PRDM14.
Biochem/physiol Actions
This antibody recognizes the N-terminus of PRDM14.
Analysis Note
Evaluated by Western Blot in human lung tissue lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected PRDM14 in 10 µg of human lung tissue lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected PRDM14 in 10 µg of human lung tissue lysate.
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Classe de stockage
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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SOX17 is a critical specifier of human primordial germ cell fate.
Irie, N; Weinberger, L; Tang, WW; Kobayashi, T; Viukov, S; Manor, YS; Dietmann, S; Hanna et al.
Cell null
Yu Kang et al.
Cell reports, 25(9), 2563-2576 (2018-11-30)
Monkeys are an optimal model species for developing stem cell therapies. We previously reported generating chimeric cynomolgus monkey fetuses using dome-shaped embryonic stem cells (dESCs). However, conventional primed pluripotent stem cells (pPSCs) lack chimera competency. Here, by altering the media
Pengyi Yang et al.
Cell systems, 8(5), 427-445 (2019-05-13)
Pluripotency is highly dynamic and progresses through a continuum of pluripotent stem cell states. The two states that bookend the pluripotency continuum, naive and primed, are well characterized, but our understanding of the intermediate states and transitions between them remains
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| AB4350 | 04053252421747 |