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Merck

MAB395

Anti-Myelin Basic Protein Antibody

CHEMICON®, rat monoclonal, 14

Synonyme(s) :

MBP

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A propos de cet article

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
14, monoclonal
Technique(s):
ELISA: suitable, immunohistochemistry: suitable
Application:
ELISA, IHC
Citations:
19
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Nom du produit

Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14, culture supernatant, clone 14, Chemicon®

biological source

rat

Quality Level

antibody form

culture supernatant

antibody product type

primary antibodies

clone

14, monoclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunohistochemistry: suitable

isotype

IgG2b

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... MBP(4155)

Immunogen

Bovine myelin basic protein.
Epitope: a.a. 36-50

Application

Detect Myelin Basic Protein using this Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14 validated for use in ELISA, IH.
Immunohistochemistry (frozen sections)

ELISA

This antibody is also expected to work for Western blot. Specific testing has not been performed.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurochemistry & Neurotrophins

Biochem/physiol Actions

Reacts with a synthetic peptide corresponding to human MBP sequence 36-50 as well as intact human MBP. Numbering of MBP residues is as described by Martenson (1984). Mapped by Geyson method to FFGGDR and RFFGGO region.

Physical form

Tissue culture supernatant. Liquid containing 0.09% sodium azide.

Preparation Note

Maintain at -20° in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze-thaw cycles.

Other Notes

Replaces: MAB395

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Feng Mei et al.
Nature medicine, 20(8), 954-960 (2014-07-07)
Functional screening for compounds that promote remyelination represents a major hurdle in the development of rational therapeutics for multiple sclerosis. Screening for remyelination is problematic, as myelination requires the presence of axons. Standard methods do not resolve cell-autonomous effects and
Anzari Atik et al.
Frontiers in physiology, 10, 990-990 (2019-08-21)
Caffeine is one of the few treatments available for infants with apnea of prematurity. As the recommended dosing regimen is not always sufficient to prevent apnea, higher doses may be prescribed. However, little is currently known about the impact of
Matteo Bastiani et al.
NeuroImage, 158, 205-218 (2017-07-04)
Diffusion MRI allows us to make inferences on the structural organisation of the brain by mapping water diffusion to white matter microstructure. However, such a mapping is generally ill-defined; for instance, diffusion measurements are antipodally symmetric (diffusion along x and



Numéro d'article de commerce international

RéférenceGTIN
MAB395-1ML04053252662676