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Merck

MAB395

Anti-Myelin Basic Protein Antibody

CHEMICON®, rat monoclonal, 14

Synonyme(s) :

MBP

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A propos de cet article

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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Nom du produit

Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14, culture supernatant, clone 14, Chemicon®

biological source

rat

antibody form

culture supernatant

antibody product type

primary antibodies

clone

14, monoclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable

isotype

IgG2b

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... MBP(4155)

Application

Detect Myelin Basic Protein using this Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14 validated for use in ELISA, IH.
Immunohistochemistry (frozen sections)

ELISA

This antibody is also expected to work for Western blot. Specific testing has not been performed.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurochemistry & Neurotrophins

Biochem/physiol Actions

Reacts with a synthetic peptide corresponding to human MBP sequence 36-50 as well as intact human MBP. Numbering of MBP residues is as described by Martenson (1984). Mapped by Geyson method to FFGGDR and RFFGGO region.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Bovine myelin basic protein.
Epitope: a.a. 36-50

Other Notes

Replaces: MAB395

Physical form

Tissue culture supernatant. Liquid containing 0.09% sodium azide.

Preparation Note

Maintain at -20° in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze-thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Feng Mei et al.
Nature medicine, 20(8), 954-960 (2014-07-07)
Functional screening for compounds that promote remyelination represents a major hurdle in the development of rational therapeutics for multiple sclerosis. Screening for remyelination is problematic, as myelination requires the presence of axons. Standard methods do not resolve cell-autonomous effects and
Anzari Atik et al.
Frontiers in physiology, 10, 990-990 (2019-08-21)
Caffeine is one of the few treatments available for infants with apnea of prematurity. As the recommended dosing regimen is not always sufficient to prevent apnea, higher doses may be prescribed. However, little is currently known about the impact of
Chrysanthy Ikonomidou et al.
Neurobiology of disease, 130, 104489-104489 (2019-06-09)
Sedatives and anesthetics can injure the developing brain. They cause apoptosis of neurons and oligodendrocytes, impair synaptic plasticity, inhibit neurogenesis and trigger long-term neurocognitive deficits. The projected vulnerable period in humans extends from the third trimester of pregnancy to the
So-ichi Tamai et al.
The Journal of biological chemistry, 289(3), 1629-1638 (2013-11-28)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of motor neurons. Here we show that the basic leucine zipper transcription factor NFIL3 (also called E4BP4) confers neuroprotection in models of ALS. NFIL3 is up-regulated in primary
Matteo Bastiani et al.
NeuroImage, 158, 205-218 (2017-07-04)
Diffusion MRI allows us to make inferences on the structural organisation of the brain by mapping water diffusion to white matter microstructure. However, such a mapping is generally ill-defined; for instance, diffusion measurements are antipodally symmetric (diffusion along x and

Numéro d'article de commerce international

RéférenceGTIN
MAB395-1ML04053252662676

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