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Merck

MAB4315

Anti-STRO-1 Antibody, clone STRO-1

ascites fluid, clone STRO-1, Chemicon®

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
STRO-1, monoclonal
Species reactivity:
human, primate
Application:
FACS, IF
Citations:
21

Principaux documents

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biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

STRO-1, monoclonal

species reactivity

human, primate

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunofluorescence: suitable

input

sample type mesenchymal stem cell(s)

isotype

IgM

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Catégories apparentées

General description

STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.

Immunogen

CD34+ bone marrow cells

Application

Detect STRO-1 using this Anti-STRO-1 Antibody, clone STRO-1 validated for use in FC & IF.

Biochem/physiol Actions

Recognizes a cell surface antigen expressed by bone marrow stromal cells and stromal precursors. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors.

Analysis Note

Control
Bone marrow cultures

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Byung Cheol Kim et al.
Journal of biomedical research, 33(2), 122-130 (2019-04-24)
Despite their potential applications in future regenerative medicine, periodontal ligament stem cells (PDLSCs) are difficult to obtain in large amounts from patients. Therefore, maintaining stemness while expanding the cell numbers for medical use is the key to transitioning PDLSCs from
Jeong Seok Lee et al.
Journal of cell communication and signaling, 12(4), 661-672 (2018-05-05)
A mussel-inspired polydopamine (PDA), resulting from the oxidative polymerization of dopamine, was reported to be an attractive substrate for advancing biomaterial applications. Thus, this study determined the osteoconductive/osteoinductive properties of titanium (Ti) surfaces coated with PDA and the facilitation of
Emma L Smith et al.
Tissue engineering. Part C, Methods, 18(12), 984-994 (2012-06-14)
Enhancement and application of our understanding of skeletal developmental biology is critical to developing tissue engineering approaches to bone repair. We propose that use of the developing embryonic femur as a model to further understand skeletogenesis, and the effects of
Y Wang et al.
Cell proliferation, 47(3), 241-248 (2014-03-19)
The aim of this study was to investigate effects of mineral trioxide aggregate (MTA) on odonto/osteogenic differentiation of bone marrow stromal cells (BMSCs) from craniofacial bones. Craniofacial BMSCs were isolated from rat mandible and effects of MTA on their proliferation
Jun Shu et al.
Biological research, 48, 69-69 (2015-12-25)
Human amnion mesenchymal cells (hAMCs), isolated from the amniotic membrane of human placenta, are a unique population of mesenchymal stem cells. Recent studies demonstrated that hAMCs could inhibit the activities and functions of several immune cells. However, their effect on
Afficher tous les articles scientifiques apparentés

Contenu apparenté

Human Stem Cell Systems

As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.

MOUSE ANTI-STRO-1 MONOCLONAL ANTIBODY

Numéro d'article de commerce international

RéférenceGTIN
MAB431504053252579967

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