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16101

Resorcinol

meets analytical specification of Ph. Eur., BP, 98.5-100.5% (calc. to the dried substance)

Synonyme(s) :

1,3-Benzenediol

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A propos de cet article

Formule linéaire :
C6H4-1,3-(OH)2
Numéro CAS:
108-46-3
Poids moléculaire :
110.11
NACRES:
NA.21
PubChem Substance ID:
57647546
eCl@ss:
39023402
UNSPSC Code:
41116107
EC Number:
203-585-2
MDL number:
MFCD00002269
Beilstein/REAXYS Number:
906905
Assay:
98.5-100.5% (calc. to the dried substance)
Form:
solid
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vapor density

3.8 (vs air)

Quality Level

200

vapor pressure

1 mmHg ( 21.1 °C)

assay

98.5-100.5% (calc. to the dried substance)

form

solid

autoignition temp.

1126 °F

quality

meets analytical specification of Ph. Eur., BP

impurities

acidity or alkalinity, complies, related subst., complies, residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤0.01% free acid (as H2SO4), ≤0.01% free alkali (as NH3), ≤0.01% pyrocatechol

ign. residue

≤0.05% (as SO4)

loss

≤1.0% loss on drying (on silica gel)

bp

178 °C/16 mmHg (lit.)

mp

109-112 °C (lit.)

solubility

water: soluble

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤500 mg/kg

suitability

complies for appearance of solution, complies for identity

application(s)

pharmaceutical (small molecule)

SMILES string

Oc1cccc(O)c1

InChI

1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H

InChI key

GHMLBKRAJCXXBS-UHFFFAOYSA-N

Application

Resorcinol has been used in resorcinol staining for visualizing the gangliosides. It has also been used for estimating sialic acids by colorimetric assay.

Biochem/physiol Actions

Resorcinol is an aromatic alcohol serves as an antiseptic. It reduces pain from painful nodules in patients suffering from Hidradenitis suppurativa (HS).

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 1 Oral - STOT SE 2 Oral

target_organs

Central nervous system,Blood, Respiratory system

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

260.6 °F - closed cup

flash_point_c

127 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCN3379
BCCM6958
BCCL2735
BCCG3734
BCCL8189

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Consulter la Bibliothèque de documents

Elodie Masson et al.
The Biochemical journal, 388(Pt 2), 537-544 (2005-01-19)
Alterations in proliferation and hypertrophy of renal mesangial cells are typical features of diabetic nephropathy. The HP (hexosamine pathway) has been proposed as a biochemical hypothesis to explain microvascular alterations due to diabetic nephropathy; however, involvement of HP in the
J Boer et al.
Clinical and experimental dermatology, 35(1), 36-40 (2009-06-25)
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by abscess formation localized to apocrine sweat gland-bearing skin. The most important factor in patients' overall assessment of disease severity is pain. The duration of abscesses takes days to weeks
Ariana Kupai et al.
Frontiers in cell and developmental biology, 8, 241-241 (2020-04-25)
Lysine methylation facilitates protein-protein interactions through the activity of methyllysine (Kme) "reader" proteins. Functions of Kme readers have historically been studied in the context of histone interactions, where readers aid in chromatin-templated processes such as transcription, DNA replication and repair.
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