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Merck

31519

Ethoxyquin

PESTANAL®, analytical standard

Synonyme(s) :

6-éthoxy-1,2-dihydro-2,2,4-triméthylquinoline

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A propos de cet article

Formule empirique (notation de Hill) :
C14H19NO
Numéro CAS:
Poids moléculaire :
217.31
NACRES:
NA.24
E Number:
E324
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
202-075-7
MDL number:
Beilstein/REAXYS Number:
158223
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InChI

1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3

InChI key

DECIPOUIJURFOJ-UHFFFAOYSA-N

SMILES string

CCOc1ccc2NC(C)(C)C=C(C)c2c1

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

density

1.03 g/mL at 20 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

shipped in

wet ice

storage temp.

2-8°C

Quality Level

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Catégories apparentées

General description

Ethoxyquin (EQ), an aromatic compound, is an antioxidant mostly used in animal and fish feeds. It is seen to inhibit carcinogenic effects of polycyclic aromatic hydrocarbons. Oxidation initiated by air, light or transition metals in unsaturated lipids can be stopped from propagation by EQ.

Application

EQ has been used as external standard in the determination of EQ and its major metabolite from Atlantic salmon tissues using HPLC with fluorescence detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Light sensitive: sensitive
Air sensitive: Handle under argon

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Classe de stockage

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

The inhibitory effects of ethoxyquin on the carcinogenic action of aflatoxin B1 in rats.
Cabral JR, Neal GE.
Cancer Letters, 19(2), 125-132 (1983)
Laia Sanchez Costa et al.
Analytical methods : advancing methods and applications, 12(32), 4080-4088 (2020-08-08)
Ethoxyquin (EQ) is a quinolone commonly used as an antioxidant additive and a fungicide. However, Regulation (EU) 2017/962 suspended its authorisation as a feed additive for all animal species and categories. The aim of this study is thus to ensure
Victoria J Berdikova Bohne et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(5), 1834-1843 (2008-03-11)
The biological fate of the fish feed additive, ethoxyquin (EQ) was examined in the muscle of Atlantic salmon during 12 weeks of feeding followed by a 2 weeks depuration period. Parent EQ (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline), quinone imine (2,6-dihydro-2,2,4-trimethyl-6-quinolone), de-ethylated EQ (6-hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline) and
Victoria J Berdikova Bohne et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(5), 733-746 (2006-12-08)
The synthetic antioxidant ethoxyquin (EQ) is a widely used additive in animal feeds, including farmed fish feed. The use of EQ as food additive is prohibited and it is also undesirable in farmed meat and fish products. The possible negative
Ronald A Lubet et al.
Chemico-biological interactions, 182(1), 22-28 (2009-08-22)
Identifying agents that block tumor initiation is a goal of cancer prevention. The ability of a chemically varied group of agents to induce various drug metabolizing genes in livers of rats was examined. Sprague-Dawley rats were treated for 7 days

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