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Merck

33987

Olaquindox

VETRANAL®, analytical standard

Synonyme(s) :

N-(2-Hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide

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A propos de cet article

Formule empirique (notation de Hill) :
C12H13N3O4
Numéro CAS:
23696-28-8
Poids moléculaire :
263.25
NACRES:
NA.24
PubChem Substance ID:
329754726
UNSPSC Code:
41116107
EC Number:
245-832-7
MDL number:
MFCD00210341

Principaux documents

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InChI key

TURHTASYUMWZCC-UHFFFAOYSA-N

InChI

1S/C12H13N3O4/c1-8-11(12(17)13-6-7-16)15(19)10-5-3-2-4-9(10)14(8)18/h2-5,16H,6-7H2,1H3,(H,13,17)

SMILES string

Cc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

Catégories apparentées

General description

Olaquindox is an antibiotic veterinary drug, used as a growth promoter for pig farming.

Application

Olaquindox may be used as a reference standard in the determination of olaquindox in feed samples using matrix solid-phase dispersion extraction (MSPDE) and hydrophilic interaction ultra-high-pressure liquid chromatography (HILIC-UHPLC) with photodiode array detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

hcodes

H302,H334

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCH1618
BCBW1743

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Consulter la Bibliothèque de documents

Xu Wang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(5), 1068-1079 (2011-01-27)
To investigate the teratogenic potential and reproductive toxicity of cyadox, a growth promoting agent, Wistar rats (F(0)) were fed with diets containing cyadox (0, 50, 150 and 2500 mg/kg) or olaquindox (150 mg/kg), approximately equivalent to cyadox 5, 15, 250
Xian-Ju Huang et al.
Chemico-biological interactions, 185(3), 227-234 (2010-03-02)
Quinoxaline 1,4-dioxides (QdNOs) derivatives, the potent synthetic antibacterial group used in food-producing animals, are assumed to have pro-oxidant properties. However, how oxidative stress mediated their adrenal toxicity is far from clear. The aim of this study was to assess the
Tianci Xu et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(7), 2540-2546 (2012-04-25)
The interaction between olaquindox (OLA) and bovine serum albumin (BSA) was investigated using fluorescence, UV-vis absorption and circular dichroism (CD) spectroscopy. The results showed that the fluorescence quenching of BSA by OLA was a static quenching process induced by the
Xu Wang et al.
Regulatory toxicology and pharmacology : RTP, 59(2), 324-333 (2010-12-07)
To investigate the chronic toxicity of cyadox, a growth promoting agent, five groups of Wistar rats (30 rats/group/sex) were fed with the diets containing cyadox (0, 100, 400 and 2000 mg/kg) or olaquindox (400 mg/kg) for 78weeks. There were significant
Chunmei Song et al.
Journal of agricultural and food chemistry, 59(17), 9319-9326 (2011-08-13)
A rapid immunochromatographic lateral flow test strip of competitive format has been developed for the specific determination of olaquindox (OLA) residues in pig urine and muscle tissues. The sensitivity of the test strip was found to be 1.58 ± 0.27
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