D-sorbitol

Name: <SC>D</SC>-sorbitol
Brand: SIAL

liquid, tested according to Ph. Eur.

Synonyme(s) :

D-glucitol

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About This Item

Formule empirique (notation de Hill) :

C₆H₁₄O₆

Numéro CAS:

50-70-4

Poids moléculaire :

182.17

UNSPSC Code:

12352201

NACRES:

NA.21

PubChem Substance ID:

329770356

EC Number:

200-061-5

Beilstein/REAXYS Number:

1721899

MDL number:

MFCD00004708

Nom du produit

D-sorbitol, liquid, tested according to Ph. Eur.

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

agency

USP/NF
tested according to Ph. Eur.

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

assay

72-92%

form

liquid

impurities

28-32% water

color

white

useful pH range

5.0-7 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

water: soluble 182 g/L at 20 °C (68 °F)

Quality Level

100

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Catégories apparentées

Biologie chimique

Glucides pour la recherche biochimique

Produits biochimiques

Suppléments et réactifs pour la culture cellulaire

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Assessment of the hepatic circulation in humans: new concepts based on evidence derived from a D-sorbitol clearance method.

G Molino et al.

The Journal of laboratory and clinical medicine, 131(5), 393-405 (1998-05-30)

D-Sorbitol (SOR) is safe, is easy to measure, and has an exceptionally high extraction ratio in the normal liver of 0.93+/-0.05 (mean+/-SD). Together with the general interest in hepatic hemodynamics, these facts motivated us to review the usefulness of this

FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress.

Reddy Ranjith K Sama et al.

Journal of cellular physiology, 228(11), 2222-2231 (2013-04-30)

FUsed in Sarcoma/Translocated in LipoSarcoma (FUS/TLS or FUS) has been linked to several biological processes involving DNA and RNA processing, and has been associated with multiple diseases, including myxoid liposarcoma and amyotrophic lateral sclerosis (ALS). ALS-associated mutations cause FUS to

An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A.

Shahram Attarian et al.

Orphanet journal of rare diseases, 9, 199-199 (2014-12-19)

Charcot-Marie-Tooth type 1A disease (CMT1A) is a rare orphan inherited neuropathy caused by an autosomal dominant duplication of a gene encoding for the structural myelin protein PMP22, which induces abnormal Schwann cell differentiation and dysmyelination, eventually leading to axonal suffering

Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes.

J M van Griensven et al.

Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)

To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Single and multiple doses of tolrestat

Electrocatalytic hydrogenation and deoxygenation of glucose on solid metal electrodes.

Youngkook Kwon et al.

ChemSusChem, 6(3), 455-462 (2013-01-25)

This Full Paper addresses the electrocatalytic hydrogenation of glucose to sorbitol or 2-deoxysorbitol on solid metal electrodes in neutral media. Combining voltammetry and online product analysis with high-performance liquid chromatography (HPLC), provides both qualitative and quantitative information regarding the reaction

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