H3136
Hematoxylin
certified by the BSC
Synonyme(s) :
Natural Black 1
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A propos de cet article
Formule empirique (notation de Hill) :
C16H14O6 · xH2O
Numéro CAS:
Poids moléculaire :
302.28 (anhydrous basis)
EC Number:
208-237-3
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Colour Index Number:
75290
Beilstein/REAXYS Number:
91400
Service technique
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certified by the BSC
Quality Level
form
powder
mp
200 °C (dec.) (lit.)
solubility
ethanol: 1 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O
InChI
1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1
InChI key
WZUVPPKBWHMQCE-XJKSGUPXSA-N
Gene Information
rat ... Adora1(29290), Adora2a(25369)
General description
Hematoxylin is a basophilic dye extracted from the tree Heamatoxylum campechianum. It specifically binds to acidic compounds and thus is useful for staining cell nuclei which contain acidic substances: DNA and RNA. Hematoxylin, when oxidized forms hematein, which has thick pale blue purple colour. Hematoxylin is often used along with eosin, in histological study under light microscope.
Application
Certified for use in Weigert′s iron hematoxylin, Mayer′s hemalum, Harris hemalum and in Heidenhain′s technique
Hematoxylin has been used:
- to visualize anatomical features and to detect nucleus locus coeruleus adjacent to the periaqueductal gray region in brainstem samples
- as a nuclear counterstain to visualize the nucleus, adipocytes were counterstained with a hematoxylin reagent
- to stain lung tissue for histological analysis
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Classe de stockage
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Histologic validation of locus coeruleus MRI contrast in post-mortem tissue.
Keren NI
Neuroimage, 113, 235-235 (2015)
Expression of matrilin-2 in liver cirrhosis and hepatocellular carcinoma
Szabo E, et al.
Pathology Oncology Research, 14(1), 15-22 (2008)
S-nitrosylation of fatty acid synthase regulates its activity through dimerization.
Choi MS
Journal of Lipid Research, 57, 607-607 (2016)