P2126
L-Phenylalanine
≥98%
Synonyme(s) :
(S)-2-Amino-3-phenylpropionic acid
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A propos de cet article
Formule linéaire :
C6H5CH2CH(NH2)CO2H
Numéro CAS:
Poids moléculaire :
165.19
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-568-1
MDL number:
Beilstein/REAXYS Number:
1910408
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L-Phenylalanine, reagent grade, ≥98%
grade
reagent grade
Quality Level
assay
≥98%
form
powder or crystals
color
white to off-white
mp
270-275 °C (dec.) (lit.)
solubility
1 M NH4OH: 50 mg/mL, clear, colorless
application(s)
detection
SMILES string
N[C@@H](Cc1ccccc1)C(O)=O
InChI
1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
InChI key
COLNVLDHVKWLRT-QMMMGPOBSA-N
Application
L-Phenylalanine has been used in Fluo-4 Ca2+-assay in a study to demonstrate that G-protein coupled receptor 139 reference surrogate agonists 1a and 7c and L-phenylalanine share a common binding site. It has also been used to spike blood samples to study the effect of dried blood spots on newborn screening.
Biochem/physiol Actions
L-Phenylalanine is an essential aromatic amino acid. It has a role in metabolism as it forms a starting point for many pathways. This neutral amino acid is a precursor for tyrosine, epinephrine, dopamine and norepinephrine.
Classe de stockage
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Protein and Amino Acid Metabolism
ESSENTIALS OF MEDICINAL CHEMISTRY null
Effect of Dried Blood Spot Quality on Newborn Screening Analyte Concentrations and Recommendations for Minimum Acceptance Criteria for Sample Analysis
Roanna S. George, Stuart J. Moat
Clinical Chemistry (2016)
The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site
Anne Cathrine
Scientific Reports (2017)