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Merck

571261

Piperidine

biotech. grade, ≥99.5%

Synonyme(s) :

Hexahydropyridine

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A propos de cet article

Formule empirique (notation de Hill) :
C5H11N
Numéro CAS:
Poids moléculaire :
85.15
UNSPSC Code:
12352005
NACRES:
NA.21
PubChem Substance ID:
EC Number:
203-813-0
Beilstein/REAXYS Number:
102438
MDL number:
Assay:
≥99.5%
Grade:
biotech. grade
Technique(s):
DNA sequencing: suitable
Bp:
106 °C
Vapor pressure:
23 mmHg ( 20 °C)
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grade

biotech. grade

Quality Segment

vapor density

3 (vs air)

vapor pressure

23 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

technique(s)

DNA sequencing: suitable

impurities

<0.3% water

refractive index

n20/D 1.452 (lit.)

bp

106 °C

mp

−13 °C (lit.)

solubility

organic solvents: soluble(lit.), water: miscible(lit.)

density

0.862 g/mL at 20 °C (lit.)

λ

1 cm path, H2O reference

UV absorption

λ: 290 Amax: <1.000, λ: 370 Amax: <0.050

SMILES string

C1CCNCC1

InChI

1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2

InChI key

NQRYJNQNLNOLGT-UHFFFAOYSA-N

General description

Our biotech solvents offer exceptional quality for reliable RNA extraction, ensuring optimal laboratory performance. With low water content and minimal residue, give clean UV spectra to minimize contamination.
  • High-Quality Biotech Solvents: Designed for optimal laboratory performance with low water content and minimal residues.
  • Ideal for RNA Extraction: Essential for genetic testing and research applications like PCR.
  • Ensures Integrity of Genetic Material: Promotes reliable and reproducible results.
  • Industry Compliant: Suitable for both academic and commercial laboratories, enhancing research efficiency.

Piperidine, a heterocyclic cyclohexane is a volatile secondary amine. Maxam-Gilbert chemical method, a DNA sequencing technology employs piperidine to rupture DNA strands at damaged base site. Its crystal structure analyzed at 150K shows hydrogen bonding between NH groups. Piperidine ring forms a part of many naturally occuring alkaloids. It is prepared on an industrial scale by the hydrogenation of pyridine in the presence of nickel catalyst. The 1H NMR spectrum of piperidine has been recorded.

Application

Piperidine has been used in combination with DMF (dimethylformamide) for the removal of Fmoc (fluorenylmethyloxycarbonyl) group from the N-terminal amino group during peptide synthesis.
Fits Applied Biosystems 431 and 433A peptide synthesizers.


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Classe de stockage

3 - Flammable liquids

wgk

WGK 1

flash_point_f

60.8 °F - closed cup

flash_point_c

16 °C - closed cup



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