A1010
Arsenic(III) oxide
ReagentPlus®, ≥99.0%
Synonyme(s) :
Arsenic trioxide, Arsenous acid
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A propos de cet article
Formule empirique (notation de Hill) :
As2O3
Numéro CAS:
Poids moléculaire :
197.84
NACRES:
NA.55
PubChem Substance ID:
UNSPSC Code:
12171602
EC Number:
215-481-4
MDL number:
Assay:
≥99.0%
Form:
powder
Service technique
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Laissez-nous vous aidervapor pressure
0 hPa ( 66 °C)
Quality Level
product line
ReagentPlus®
assay
≥99.0%
form
powder
storage temp.
room temp
SMILES string
O=[As]O[As]=O
InChI
1S/As2O3/c3-1-5-2-4
InChI key
IKWTVSLWAPBBKU-UHFFFAOYSA-N
General description
Arsenic(III) oxide, also known as arsenic trioxide, is an amphoteric oxide that serves as a raw material for the synthesis of several arsenic-based compounds. It is utilized to decolorize glasses and enamels. Its efficacy in treating in acute promyelocytic leukaemia (APL) has been investigated.
Application
Arsenic(III) oxide was used in a study detailing the effect of arsenic trioxide in combination with γ-irradiation to elucidate the hemoglobin (Hb).
Biochem/physiol Actions
Very potent agent against acute promyelocytic leukemia (APL). Causes skin, lung and bladder cancer.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1
target_organs
Respiratory system,Cardio-vascular system,Gastrointestinal tract
Classe de stockage
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Contenu apparenté
Product Information Sheet
E Lengfelder et al.
Leukemia, 26(3), 433-442 (2011-09-10)
Arsenic trioxide (ATO) is presently the most active single agent in the treatment of acute promyelocytic leukemia (APL). This review provides insights into the mode of action and the pharmacological properties of ATO, and summarizes the most relevant results of
Combined effect of arsenic trioxide and radiation on physical properties of hemoglobin biopolymer.
Saad-El-Din AA, et al.
Journal of Radiation Research and Applied Sciences, 7(2), 411-416 (2014)
Wilson H Miller et al.
Cancer research, 62(14), 3893-3903 (2002-07-19)
Arsenic trioxide has shown substantial efficacy in treating both newly diagnosed and relapsed patients with acute promyelocytic leukemia (APL). As a single agent, it induces complete remissions, causing few adverse effects and only minimal myelosuppression. These successes have prompted investigations