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50246

Poly(éthylene glycol)-blocage-poly(propylène glycol)-blocage-poly(éthylene glycol)

Synonyme(s) :

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Lμtrol micro 127

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A propos de cet article

Numéro CAS:
9003-11-6
UNSPSC Code:
12161900
NACRES:
NA.25
MDL number:
MFCD00082049
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mol wt

~9840-14600 g/mol

Quality Level

100

composition

oxyethylene content, 71.5-74.9%

impurities

≤0.25% ethylene glycol and diethylene glycol, ≤0.4% total ash, ≤0.75% water, ≤1 ppm ethylene oxide, ≤2 ppm arsenic, ≤20 ppm heavy metals, 50-125 ppm butylhydroxytoluene

ign. residue

≤0.30%

color

APHA: ≤120

particle size distribution

, coeff var ≤10% (residue, No. 140 USS), , coeff var ≤50% (residue, No. 270 USS)

pH

5.0-7.5(1:10), 5.0-7.5(1:40)

suitability

complies for Infrared spectrum

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

Application

The Poloxamer 407 grades are poloxamers from the extensive line of Pluronic® block copolymers. They are widely used as a thickening agent and gel binder.

Analysis Note

residual solvents (GLC-HS)
1,4-dioxane ≤5 ppm, ethylene glycol ≤620 ppm ( verified on random samples only)

Other Notes

average molecular weight/mass 9840-14600 g/mol; average molecular mass 10000-14600 g/mol

Legal Information

Pluronic is a registered trademark of BASF

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
BCCN7986
BCCL1662
BCCH9437
BCCF0240
BCCB5869

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Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
Laurien Buitinga et al.
Clinical and experimental rheumatology, 29(5), 783-789 (2011-10-04)
The Time Trade-Off (TTO) is an instrument used for valuing health-related quality of life. This study evaluated the test-retest reliability of a computer TTO in rheumatoid arthritis (RA), and compared the computer with the interview TTO regarding feasibility and agreement.
Xijun Zhang et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)
This study examined the effect of P85 (a pluronic block copolymer) and microbubble (MB) ultrasound contrast agents under ultrasound irradiation on gene transfection and expression. The pEGFP plasmids that can encode enhanced green fluorescent protein (pEGFP) served as a report
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