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Merck

A273

Monoclonal Anti-Na+/K+ ATPase (α3 Subunit) antibody produced in mouse

1 mg/mL, clone XVIF9-G10, ascites fluid

Synonyme(s) :

Anti-AHC2, Anti-ATP1A1, Anti-CAPOS, Anti-DEE99, Anti-DYT12, Anti-RDP

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
XVIF9-G10, monoclonal
Application:
IHC (f), WB
Citations:
5
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biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

XVIF9-G10, monoclonal

mol wt

antigen ~110 kDa

species reactivity

human, rat, monkey, sheep, rabbit, guinea pig, canine

concentration

1 mg/mL

technique(s)

immunohistochemistry (frozen sections): 3 μg, western blot: 1 μg

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ATP1A3(478)
rat ... Atp1a3(24213)

General description

Mouse monoclonal anti-Na+/K+ ATPase (α3 subunit) antibody reacts specifically with Na+/K+ ATPase α3 subunit. By immunoblotting, the product reacts with human, monkey, sheep, canine, rabbit, guinea pig and rat tissues in which the α3 subunit is expressed. Immunohistochemical staining is consistent with the plasma membrane localization of Na+/K+ ATPase.
Na+/K+ transporting ATPase subunit α1 is an ion transport pump critical for maintaining the gradient of Na and K ions across the plasma membrane.

Immunogen

canine cardiac microsomes.

Application

Mouse monoclonal anti-Na+/K+ ATPase (α3 subunit) antibody has been used for chemiluminescent western blot analysis. The product has also been used for co-immunoprecipitation applications.

Physical form

Solution in phosphate buffered saline containing 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Consulter la Bibliothèque de documents

Emmanuelle Berret et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(7), 3067-3078 (2013-02-15)
The median preoptic nucleus (MnPO) holds a strategic position in the hypothalamus. It is adjacent to the third ventricle; hence, it can directly access the ionic composition of the CSF. MnPO neurons play a critical role in hydromineral homeostasis regulation
Athina Zouzoulas et al.
The Journal of biological chemistry, 281(13), 8539-8544 (2006-02-01)
The gamma modulator (FXYD 2) is a member of the FXYD family of single transmembrane proteins that modulate the kinetic behavior of Na,K-ATPase. This study concerns the identification of regions in the alpha subunit that are important for its functional
K Pather et al.
Thrombosis research, 177, 51-58 (2019-03-10)
Platelet-tumour cell interaction is implicated in the initiation of breast cancer-associated thrombosis, with hormone-therapy (Tamoxifen/Anastrozole), increasing this risk. However, recent in vitro research indicates that Tamoxifen inhibits platelet activation, while the effects of Anastrozole on platelet activation are not well
Steven J Clapcote et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(33), 14085-14090 (2009-08-12)
In a mouse mutagenesis screen, we isolated a mutant, Myshkin (Myk), with autosomal dominant complex partial and secondarily generalized seizures, a greatly reduced threshold for hippocampal seizures in vitro, posttetanic hyperexcitability of the CA3-CA1 hippocampal pathway, and neuronal degeneration in
Paola Vagni et al.
Nature communications, 13(1), 3678-3678 (2022-06-28)
Retinal prostheses hold the potential for artificial vision in blind people affected by incurable diseases of the outer retinal layer. Available technologies provide only a small field of view: a significant limitation for totally blind people. To overcome this problem

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