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Merck

A7791

N-Acetyl-D-lactosamine

≥98% (TLC)

Synonyme(s) :

β-D-Gal-(1→4)-D-GlcNAc, 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, LN, N-Acetyl-4-O-(β-D-galactopyranosyl)-D-glucosamine

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A propos de cet article

Formule empirique (notation de Hill) :
C14H25NO11
Numéro CAS:
Poids moléculaire :
383.35
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
96808
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Quality Level

assay

≥98% (TLC)

form

powder

optical activity

[α]25/D 27.5 to 33.5 °, c = 0.5% (w/v) in water

technique(s)

thin layer chromatography (TLC): suitable

impurities

≤8% water

color

white

mp

170 -185  °C ((338 - 365 °F ))

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@@H]1O

InChI

1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13?,14+/m1/s1

InChI key

KFEUJDWYNGMDBV-RPHKZZMBSA-N

Application

N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.
Useful in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.

Preparation Note

Synthetic

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Consulter la Bibliothèque de documents

Frank Liang et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 25(12), 2635-2647 (2017-09-30)
mRNA vaccines are rapidly emerging as a powerful platform for infectious diseases because they are well tolerated, immunogenic, and scalable and are built on precise but adaptable antigen design. We show that two immunizations of modified non-replicating mRNA encoding influenza
Fumi Kato et al.
Breast cancer (Tokyo, Japan), 26(5), 628-636 (2019-04-03)
We investigated the usefulness of the minimum ADC value of primary breast lesions for predicting axillary lymph node (LN) status in luminal A-like breast cancers with clinically negative nodes in comparison with the mean ADC. Forty-four luminal A-like breast cancers
Lital Sever et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(33), 16489-16496 (2019-07-28)
SLAMF9 belongs to the conserved lymphocytic activation molecule family (SLAMF). Unlike other SLAMs, which have been extensively studied, the role of SLAMF9 in the immune system remained mostly unexplored. By generating CRISPR/Cas9 SLAMF9 knockout mice, we analyzed the role of
Fumiko Suenaga et al.
Journal of immunology (Baltimore, Md. : 1950), 194(1), 398-406 (2014-11-26)
Graft-versus-host disease (GVHD) is a major risk factor for prolonged humoral immunodeficiency and vaccine unresponsiveness after allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the underlying mechanisms for this immunodeficiency are poorly understood. In this article, we describe previously overlooked impacts
Roman Sarkar et al.
Journal of immunology (Baltimore, Md. : 1950), 203(5), 1325-1337 (2019-07-25)
In this study, we investigated the response of myeloid-derived suppressor cells (MDSCs) during the pathogenesis of an immunoblinding disease of the cornea caused by HSV type 1 infection. We also measured the anti-inflammatory potential of in vitro-differentiated MDSCs in dampening

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