B4429
BIS-TRIS
BioPerformance Certified, suitable for cell culture, suitable for insect cell culture, ≥98.0%
Synonyme(s) :
2,2-Bis(hydroxyméthyl)-2,2′,2″-nitrilotriéthanol, 2-Bis(2-hydroxyéthyl)amino-2-(hydroxyméthyl)-1,3-propanediol, Bis(2-hydroxyéthyl)amino-tris(hydroxyméthyl)méthane
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A propos de cet article
Formule empirique (notation de Hill) :
C8H19NO5
Numéro CAS:
Poids moléculaire :
209.24
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
230-237-7
Beilstein/REAXYS Number:
2205275
MDL number:
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Laissez-nous vous aiderNom du produit
BIS-TRIS, BioPerformance Certified, suitable for cell culture, suitable for insect cell culture, ≥98.0%
InChI key
OWMVSZAMULFTJU-UHFFFAOYSA-N
InChI
1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2
SMILES string
OCCN(CCO)C(CO)(CO)CO
grade
BioPerformance Certified
assay
≥98.0%
form
crystalline powder
technique(s)
cell culture | insect: suitable
cell culture | mammalian: suitable
impurities
endotoxin and total aerobic microbial count, tested
useful pH range
5.8-7.2
pKa (25 °C)
6.5
mp
104 °C
solubility
H2O: 500 mg/mL, clear, colorless to very faintly yellow
anion traces
≤5 ppm
suitability
suitable for supravital staining of living blood cells
application(s)
diagnostic assay manufacturing
Quality Level
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Application
- A new test for the laboratory diagnosis of spherocytosis : cette étude présente un nouveau test diagnostique basé sur le tampon BIS-TRIS, visant à améliorer la détection et la caractérisation de la sphérocytose en milieu clinique. La stabilité du tampon et son pH optimal le rendent compatible pour des analyses de routine dans les laboratoires cliniques, garantissant des résultats exacts et reproductibles (Vettore et al., 1984).
Other Notes
Comparez facilement les spécifications des différents produits à base de BIS-TRIS grâce au Tableau de spécification du BIS-TRIS.
Features and Benefits
Features:
- Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
- Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
- M-Clarity™ Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity™ Program
- Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
- Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
- Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
- Site quality assessment
- ISO 9001 certificate
- Detailed product specifications
- Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)
- Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
- Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
- Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
- Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
- Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
- Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.
General description
Bis-Tris is a zwitterionic buffer that is used in biochemistry and molecular biology research. It is structurally analogous to the the Good buffers that were developed to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The useful pH range of Bis-Tris is 5.8 - 7.2.
Legal Information
M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Classe de stockage
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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