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Merck

C5042

Cresyl Violet acetate

Dye content, ~70%, certified by the Biological Stain Commission, powder

Synonyme(s) :

9-Amino-5-imino-5H-benzo[a]phenoxazine acetate salt

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About This Item

Formule empirique (notation de Hill) :
C18H15N3O3
Numéro CAS:
Poids moléculaire :
321.33
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
234-043-3
MDL number:

Nom du produit

Cresyl Violet acetate, certified by the BSC

InChI key

ORIKHDNZZCTIAD-UHFFFAOYSA-N

InChI

1S/C16H11N3O.C2H4O2/c17-9-5-6-13-14(7-9)20-15-8-12(18)10-3-1-2-4-11(10)16(15)19-13;1-2(3)4/h1-8,17H,18H2;1H3,(H,3,4)

SMILES string

CC(O)=O.Nc1cc2OC3=CC(=N)C=CC3=Nc2c4ccccc14

agency

certified by the BSC

form

powder

composition

Dye content, ~70%

technique(s)

microbe id | staining: suitable

color

dark green

mp

140-143 °C (lit.)

solubility

H2O: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

Certified for Nissl staining of paraffin sections of spinal cord and brain and to stain cartilage and mast cell granules.
Cresyl Violet acetate has been used in Nissl staining of sections of the spinal cord and brain. It is also suitable for the demonstration of nuclei and Nissl substance in neuroanatomical investigations. Additional applications of Cresyl violet include staining of sex chromatin, identification of Helicobacter, and diagnostically as a vital stain in endoscopic procedures.

General description

Cresyl violet acetate, also known as oxazine 9, is a small diaminobenzooxazine dye that has a planar conjugated system of moderate size.

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

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Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-? Clearance.
Gontier G, et al.
The Journal of Neuroscience, 35, 11500-11513 (2015)
Hyo Jeong Yong et al.
Scientific reports, 10(1), 3969-3969 (2020-03-04)
Neurodevelopment and mature brain function are spatiotemporally regulated by various cytokines and chemokines. The chemokine-like neuropeptide FAM19A1 is a member of family with sequence similarity 19 (FAM19), which is predominantly expressed in the brain. Its highly conserved amino acid sequence
Rat hair follicle stem cells differentiate and promote recovery following spinal cord injury.
Najafzadeh N, et al.
Neural Regeneration Research, 8, 3365-3372 (2013)
Luc Joyeux et al.
Scientific reports, 9(1), 9327-9327 (2019-06-30)
A randomized trial demonstrated that fetal spina bifida (SB) repair is safe and effective yet invasive. New less invasive techniques are proposed but are not supported by adequate experimental studies. A validated animal model is needed to bridge the translational

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