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Merck

C6594

Anticorps anti-c-Myc

clone 9E10, purified immunoglobulin, buffered aqueous solution

Synonyme(s) :

Anti-c-Myc

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A propos de cet article

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
CY3 conjugate
Clone:
9E10, monoclonal
Application:
direct immunofluorescence
Species reactivity:
human
Citations:
24
Technique(s):
direct immunofluorescence: 1:50 using formalin-fixed, paraffin-embedded human colon carcinoma tissue
Uniprot accession no.:
P01106

Principaux documents

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Nom du produit

Anticorps anti-c-Myc, clone 9E10, purified immunoglobulin, buffered aqueous solution

biological source

mouse

conjugate

CY3 conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

9E10, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

direct immunofluorescence: 1:50 using formalin-fixed, paraffin-embedded human colon carcinoma tissue

UniProt accession no.

P01106

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

200

Gene Information

human ... MYC(4609)

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Catégories apparentées

Immunogen

peptide synthétique de la protéine p62c-Myc humaine.

Application

Monoclonal Anti-c-MycCy3™ antibody produced in mouse has been used in:
  • western blotting
  • immunocytochemistry
  • Immunofluorescence

Biochem/physiol Actions

The encoded protein is involved in cell proliferation, growth and apoptosis. The c-myc gene has been implicated in the development of a number of neoplasms in a variety of avian and mammalian species. The human c-myc protooncogene is the cellular homolog of the avian v-myc gene found in several leukemogenic retroviruses. Increased expression of the cellular oncogene c-myc has been described in a variety of human tumors, occurring by several different mechanisms, including gene amplification and chromosomal translocation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-Myc gene encodes a polypeptide with a predicted molecular weight of 49 kDa.

Physical form

Solution in 0.01 M sodium phosphate buffered saline containing 1% bovine serum albumin and 15 mM sodium azide.

Legal Information

Cy3 is a trademark of Cytiva

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Classe de stockage

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000409210
0000400143
0000409210
0000400143
0000192563

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Joe DeBartolo et al.
PLoS computational biology, 10(6), e1003693-e1003693 (2014-06-27)
Programmed cell death is regulated by interactions between pro-apoptotic and prosurvival members of the Bcl-2 family. Pro-apoptotic family members contain a weakly conserved BH3 motif that can adopt an alpha-helical structure and bind to a groove on prosurvival partners Bcl-xL
Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms
Shimazu S, et al.
Cancer Science, 102(11), 2097-2102 (2011)
Genetic alteration of chromosome 8 is a common feature of human mammary epithelial cell lines transformed in vitro with benzo [a] pyrene
Caruso JA, et al.
Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis, 473(1), 85-99 (2001)
Meirav Noach-Hirsh et al.
Molecular & cellular proteomics : MCP, 14(10), 2824-2832 (2015-08-16)
Protein post-translational modifications mediate dynamic cellular processes with broad implications in human disease pathogenesis. There is a large demand for high-throughput technologies supporting post-translational modifications research, and both mass spectrometry and protein arrays have been successfully utilized for this purpose.
Human MAMLD1 gene variations seem not sufficient to explain a 46, XY DSD phenotype
Camats N, et al.
PLoS ONE, 10(11), e0142831-e0142831 (2015)
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Contenu apparenté

Data Sheet - C6594

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