D6875

21-Hydroxyprogesterone

Name: 21-Hydroxyprogesterone
Brand: SIGMA

synthetic (organic), ≥97% (HPLC), Mineralocorticoid, powder

Synonyme(s) :

21-hydroxy-4-pregnène-3,20-dione, Composé désoxy B de Kendall, DOC, Désoxycortone

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About This Item

Formule empirique (notation de Hill) :

C₂₁H₃₀O₃

Numéro CAS:

64-85-7

Poids moléculaire :

330.46

NACRES:

NA.77

PubChem Substance ID:

24894056

UNSPSC Code:

12352200

EC Number:

200-596-4

MDL number:

MFCD00003661

Beilstein/REAXYS Number:

2062123

Nom du produit

21-Hydroxyprogesterone, ≥97% (HPLC)

InChI key

ZESRJSPZRDMNHY-YFWFAHHUSA-N

InChI

1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(=O)CO

biological source

synthetic (organic)

sterility

non-sterile

assay

≥97% (HPLC)

form

powder

solubility

ethanol: 50 mg/mL, clear, colorless to very faintly yellow

shipped in

ambient

storage temp.

room temp

Quality Level

200

Gene Information

human ... SERPINA6(866)

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Catégories apparentées

Petites molécules bioactives

pictograms

GHS08

signalword

Warning

hcodes

H351,H373

pcodes

P201 - P308 + P313

Hazard Classifications

Carc. 2 - STOT RE 2

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Proteomic changes driven by urban pollution suggest particulate matter as a deregulator of energy metabolism, mitochondrial activity, and oxidative pathways in the rat brain.

J E Araújo et al.

The Science of the total environment, 687, 839-848 (2019-08-16)

The adverse effects of air pollution have been long studied in the lung and respiratory systems, but the molecular changes that this causes at the central nervous system level have yet to be fully investigated and understood. To explore the

Extensive functional redundancy in the regulation of Candida albicans drug resistance and morphogenesis by lysine deacetylases Hos2, Hda1, Rpd3 and Rpd31.

Xinliu Li et al.

Molecular microbiology, 103(4), 635-656 (2016-11-22)

Current treatment efforts for fungal infections are hampered by the limited availability of antifungal drugs and by the emergence of drug resistance. A powerful strategy to enhance the efficacy of antifungal drugs is to inhibit the molecular chaperone Hsp90. Hsp90

The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells.

Francesca Zalfa et al.

Cell death & disease, 8(11), e3169-e3169 (2017-11-17)

The fragile X mental retardation protein (FMRP) is lacking or mutated in patients with the fragile X syndrome (FXS), the most frequent form of inherited intellectual disability. FMRP affects metastasis formation in a mouse model for breast cancer. Here we

Different Bacterial Communities Involved in Peptide Decomposition between Normoxic and Hypoxic Coastal Waters.

Shuting Liu et al.

Frontiers in microbiology, 8, 353-353 (2017-03-23)

Proteins and peptides are key components of the labile dissolved organic matter pool in marine environments. Knowing which types of bacteria metabolize peptides can inform the factors that govern peptide decomposition and further carbon and nitrogen remineralization in marine environments.

In vivo reprogramming drives Kras-induced cancer development.

Hirofumi Shibata et al.

Nature communications, 9(1), 2081-2081 (2018-05-29)

The faithful shutdown of the somatic program occurs in the early stage of reprogramming. Here, we examined the effect of in vivo reprogramming on Kras-induced cancer development. We show that the transient expression of reprogramming factors (1-3 days) in pancreatic

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