G2128
L-Glutamic acid hydrochloride
≥99% (HPLC), kainate, NMDA, and quisqualate agonist
Synonyme(s) :
(S)-2-Aminoglutaric acid, (S)-2-Aminopentanedioic acid ammonium salt, Glu HCl
Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
Changer de vue
A propos de cet article
Formule empirique (notation de Hill) :
C5H9NO4 · HCl
Numéro CAS:
Poids moléculaire :
183.59
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
205-315-9
MDL number:
Beilstein/REAXYS Number:
3565569
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderNom du produit
L-Glutamic acid hydrochloride, ≥99% (HPLC)
Quality Level
assay
≥99% (HPLC)
SMILES string
Cl.N[C@@H](CCC(O)=O)C(O)=O
InChI
1S/C5H9NO4.ClH/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);1H/t3-;/m0./s1
InChI key
RPAJSBKBKSSMLJ-DFWYDOINSA-N
Gene Information
human ... GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIK5(2901)
General description
L-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.
Application
L-Glutamic acid hydrochloride has been used as a nutrient additive to study the effect of increased dissolved inorganic nitrogen (DIN) on the uptake of dissolved organic nitrogen (DON) and dissolved organic carbon (DOC), in a nitrogen-limited headwater forest stream.
Biochem/physiol Actions
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.
L-glutamate plays key roles in development, learning, memory, plasticity and cognition. It plays crucial role in the pathogenesis of neuropathological diseases such as epilepsy, schizophrenia, stroke, ischemia, ALS (amyotrophic lateral sclerosis), Huntington′s disease and Parkinson′s disease. Glutamate is also responsible for the activation of long-term potentiation (LTP) and long-term depression (LTD). Induction of glutamate receptors plays a key role in the pathophysiology of migraine.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1
Classe de stockage
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Contenu apparenté
Product Information Sheet
Coupled cycling of dissolved organic nitrogen and carbon in a forest stream.
Brookshire E N J et al
Ecology, 86(9), 2487-2496 (2005)
B K Day et al.
Journal of neurochemistry, 96(6), 1626-1635 (2006-01-31)
L-glutamate (Glu) is the predominant excitatory neurotransmitter in the mammalian central nervous system. It plays major roles in normal neurophysiology and many brain disorders by binding to membrane-bound Glu receptors. To overcome the spatial and temporal limitations encountered in previous
Martina Curto et al.
The journal of headache and pain, 17, 47-47 (2016-05-01)
Activation of glutamate (Glu) receptors plays a key role in the pathophysiology of migraine. Both NMDA and metabotropic Glu receptors are activated or inhibited by metabolites of the kynurenine pathway, such as kynureninic acid (KYNA), quinolinic acid (QUINA), and xanthurenic