H3398
DL-β-Hydroxylauric acid
≥99% (GC)
Synonyme(s) :
3-Hydroxydodecanoic acid
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A propos de cet article
Formule empirique (notation de Hill) :
C12H24O3
Numéro CAS:
Poids moléculaire :
216.32
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
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MUCMKTPAZLSKTL-UHFFFAOYSA-N
SMILES string
CCCCCCCCCC(O)CC(O)=O
InChI
1S/C12H24O3/c1-2-3-4-5-6-7-8-9-11(13)10-12(14)15/h11,13H,2-10H2,1H3,(H,14,15)
assay
≥99% (GC)
form
solid
functional group
carboxylic acid
lipid type
saturated FAs
shipped in
ambient
storage temp.
2-8°C
Quality Level
Catégories apparentées
Biochem/physiol Actions
DL-3-Hydroxydodecanoic acid (3HDD) is a racemic mixture of D- and L-3HDD. 3-hydroxydodecanoic acid is found as a monomer in the construction of polyhydroxyalkanoates. 3HDD is used to study the roles of β-hydroxy fatty acids in chronic inflammation and insulin resistance and the biosynthesis of diffusible signal factors involved in quorum sensing.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Classe de stockage
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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K Kunii et al.
Microbios, 105(412), 153-161 (2001-06-21)
The Gram-negative bacterium Acinetobacter species ODB-L2 produces lipopolysaccharide (LPS) in culture broth. The LPS could not be purified by conventional extraction methods using 90% phenol/water or 90% phenol/chloroform/petroleum ether mixed solvent. Extraction was achieved employing an admixture of chloroform, ethanol
J S Chickos et al.
Journal of clinical laboratory analysis, 16(2), 115-120 (2002-04-12)
Current diagnostic tests to detect disorders of fatty acids metabolism, such as long-chain hydroxyacyl CoA dehydrogenase deficiency (LCHAD), are hampered by insensitivity or a long delay time required for results. Children with LCHAD deficiency are known to excrete 3-hydroxydicarboxylic acids
P M Jones et al.
Clinical chemistry, 47(7), 1190-1194 (2001-06-28)
The diagnosis of long-chain L-3-hydroxy-acyl-coenzyme A dehydrogenase (LCHAD) deficiency frequently requires the study of cultured fibroblasts. We developed such a test that does not require disruption and loss of the cells. We measured free 3-hydroxy fatty acids (3-OHFAs) in media
Anelise M Tonin et al.
Life sciences, 86(21-22), 825-831 (2010-04-20)
We investigated the in vitro effects of 3-hydroxydodecanoic (3HDA), 3-hydroxytetradecanoic (3HTA) and 3-hydroxypalmitic (3HPA) acids, which accumulate in tissues of patients affected by mitochondrial trifunctional protein (MTP) and isolated long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiencies, on various parameters of energy homeostasis
Shao-Ping Ouyang et al.
Biomacromolecules, 8(8), 2504-2511 (2007-07-31)
Pseudomonas putida KT2442 produces medium-chain-length (MCL) polyhydroxyalkanoates (PHA) consisting of 3-hydroxyhexanoate (HHx), 3-hydroxyoctanoate (HO), 3-hydroxydecanoate (HD), and 3-hydroxydodecanoate (HDD) from a wide-range of carbon sources. In this study, fadA and fadB genes encoding 3-ketoacyl-CoA thiolase and 3-hydroxyacyl-CoA dehydrogenase in P.
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