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Merck

H7509

(Hydroxypropyl)methyl cellulose

viscosity 2,600-5,600 cP, 2 % in H2O(20 °C)(lit.)

Synonyme(s) :

2-Hydroxypropyl methyl cellulose ether

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A propos de cet article

Numéro CAS:
9004-65-3
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
MFCD00131360

Principaux documents

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Nom du produit

(Hydroxypropyl)methyl cellulose, viscosity 2,600-5,600 cP, 2 % in H2O(20 °C)(lit.)

SMILES string

O3[C@H]([C@@H]([C@H]([C@@H]([C@H]3COCC(O)C)OCC(O)C)OCC(O)C)OCC(O)C)O[C@@H]4[C@H](O[C@H]([C@@H]([C@H]4OCC(O)C)OCC(O)C)OCC(O)C)COCC(O)C.O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1COC)OC)OC)OC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OC)OC)OC)COC

InChI

1S/C36H70O19.C20H38O11/c1-19(37)9-45-17-27-29(47-11-21(3)39)31(48-12-22(4)40)34(51-15-25(7)43)36(54-27)55-30-28(18-46-10-20(2)38)53-35(52-16-26(8)44)33(50-14-24(6)42)32(30)49-13-23(5)41;1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-

InChI key

PUSNGFYSTWMJSK-GSZQVNRLSA-N

biological source

plant

form

powder

mol wt

~86 kDa

color

white to off-white

viscosity

2,600-5,600 cP, 2 % in H2O(20 °C)(lit.)

solubility

water: 10 mg/mL, clear to very slightly hazy, colorless

storage temp.

room temp

Quality Level

200

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Catégories apparentées

Application

(Hydroxypropyl)methyl cellulose (HPMC) has been used:
  • as a viscosity modifier in the preparation of printable ink
  • as a viscosifier in the preparation of hydroxyapatite (HAP) suspension
  • in the preparation of HPMC gels and composite gels

Thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid.

Biochem/physiol Actions

(Hydroxypropyl)methylcelluloses (HPMCs) act as suspension aids, surfactants, lubricants, protective colloids, and emulsifiers. Additionally, solutions of these polymers show thermal gelation properties. They are generally used as binders, thickeners, film formers, and water retention agents. HPMC also elicits surface-active properties.

Features and Benefits

Dissolves in water, undergoes reversible gelation upon heating, non-ionic, does not complex with ionic species and is surface active and enzyme resistant. Solutions are pseudoplastic.

General description

(Hydroxypropyl)methylcellulose (HPMC) is a water-soluble polymer derived from cellulose. This polysaccharide forms colloids when dissolved in water. HPMC is a hydrocolloid produced artificially from natural substances. It consists of 28-30% methoxyl content and 7-12% of hydroxypropoxyl content.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCM8182
BCCL9889
BCCK4125
BCCK6407
BCCH0551

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Alexandre Goyon et al.
Electrophoresis, 39(16), 2083-2090 (2018-05-19)
The determination of mAb critical quality attributes (CQA) is crucial for their successful application in health diseases. A generic CZE method was developed for the high-resolution separation of various mAb charge variants, which are often recognized as important CQA. A
Jenny Högström et al.
Cancer research, 78(20), 5820-5832 (2018-08-30)
The homeobox transcription factor PROX1 is induced by high Wnt/β-catenin activity in intestinal adenomas and colorectal cancer, where it promotes tumor progression. Here we report that in LGR5+ colorectal cancer cells, PROX1 suppresses the Notch pathway, which is essential for
Bernd Moritz et al.
Electrophoresis, 38(24), 3136-3146 (2017-09-10)
CZE is a well-established technique for charge heterogeneity testing of biopharmaceuticals. It is based on the differences between the ratios of net charge and hydrodynamic radius. In an extensive intercompany study, it was recently shown that CZE is very robust
Mylène Tajan et al.
Nature communications, 12(1), 366-366 (2021-01-16)
Many tumour cells show dependence on exogenous serine and dietary serine and glycine starvation can inhibit the growth of these cancers and extend survival in mice. However, numerous mechanisms promote resistance to this therapeutic approach, including enhanced expression of the de
Jane W Agger et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(17), 6287-6292 (2014-04-16)
The recently discovered lytic polysaccharide monooxygenases (LPMOs) are known to carry out oxidative cleavage of glycoside bonds in chitin and cellulose, thus boosting the activity of well-known hydrolytic depolymerizing enzymes. Because biomass-degrading microorganisms tend to produce a plethora of LPMOs
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Product Information Sheet - H7509

Product Information Sheet

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