H7750
DL-Histidine
≥99% (TLC), suitable for ligand binding assays
Synonyme(s) :
(±)-2-Amino-3-(4-imidazolyl)propionic acid
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A propos de cet article
Formule empirique (notation de Hill) :
C6H9N3O2
Numéro CAS:
Poids moléculaire :
155.15
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
225-660-9
MDL number:
Beilstein/REAXYS Number:
7800
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DL-Histidine, ≥99% (TLC)
assay
≥99% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
mp
273 °C (dec.) (lit.)
solubility
0.5 M HCl: soluble
application(s)
peptide synthesis
SMILES string
NC(Cc1c[nH]cn1)C(O)=O
InChI
1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)
InChI key
HNDVDQJCIGZPNO-UHFFFAOYSA-N
Application
DL-Histidine is the mixed isomer of D- and L-histidine. DL-Histidine may be used to evaluate the efficiency of amino acid chiral ligand exchange media and systems and in running buffers for capillary electrophoresis.
DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).
Biochem/physiol Actions
L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.
Classe de stockage
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Fouling behaviour of polyethersulfone UF membranes made with different PVP
J.Marchese
Journal of Membrane Science , 211, 1-11 (2009)
Worapan Pormsila et al.
Electrophoresis, 32(8), 884-889 (2011-03-12)
The quantification of plasma lactate and evaluation of the lactate threshold by CE with capacitively coupled contactless conductivity is demonstrated. The only sample preparation needed was deproteinization with a ACN/methanol mixture. A solution of 10 mmol/L 2-morpholinoethanesulfonic acid monohydrate, 10
Yoshikazu Tsukasaki et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(45), 16011-16016 (2014-10-31)
The cadherins Fat and Dachsous regulate cell polarity and proliferation via their heterophilic interactions at intercellular junctions. Their ectodomains are unusually large because of repetitive extracellular cadherin (EC) domains, which raises the question of how they fit in regular intercellular