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Merck

I2149

Hemagglutinin Peptide

≥97% (HPLC), powder, Influenza

Synonyme(s) :

Anti-HA, HA tag peptide, HA1 fragment 98-106, Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala

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A propos de cet article

Formule empirique (notation de Hill) :
C53H67N9O17
Numéro CAS:
92000-76-5
Poids moléculaire :
1102.15
UNSPSC Code:
12352202
PubChem Substance ID:
329815363
NACRES:
NA.56
MDL number:
MFCD01310914

Principaux documents

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Nom du produit

Influenza Hemagglutinin (HA) Peptide, ≥97% (HPLC)

SMILES string

CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc5ccc(O)cc5)C(=O)N[C@@H](C)C(O)=O

InChI key

HVLSXIKZNLPZJJ-TXZCQADKSA-N

InChI

1S/C53H67N9O17/c1-27(2)44(52(77)62-21-5-7-41(62)50(75)59-38(25-42(66)67)47(72)56-36(45(70)55-28(3)53(78)79)23-30-10-16-33(64)17-11-30)60-48(73)39(26-43(68)69)57-46(71)37(24-31-12-18-34(65)19-13-31)58-49(74)40-6-4-20-61(40)51(76)35(54)22-29-8-14-32(63)15-9-29/h8-19,27-28,35-41,44,63-65H,4-7,20-26,54H2,1-3H3,(H,55,70)(H,56,72)(H,57,71)(H,58,74)(H,59,75)(H,60,73)(H,66,67)(H,68,69)(H,78,79)/t28-,35-,36-,37-,38-,39-,40-,41-,44-/m0/s1

biological source

synthetic

assay

≥97% (HPLC)

form

powder

mol wt

1102.15 Da

technique(s)

protein extraction: suitable

storage temp.

−20°C

Quality Level

200

Application

Influenza Hemagglutinin (HA) Peptide may be used in immunoblotting. It may also be used to to elute HA-tagged fusion proteins from an affinity column of Monoclonal Anti-HA agarose.

General description

Influenza Hemagglutinin (HA) peptide is a synthetic peptide with an amino acid sequence of N-Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala-C. This corresponds to amino acids 98-106 of the human influenza virus hemagglutinin. The HA Peptide is used for competing out the anti-HA antibody binding to HA-tagged fusion proteins in immunoassays. The successful inhibition of antibody binding by HA peptide demonstrates binding is specific.

Other Notes

Lyophilized from 0.1% TFA in H2O

Preparation Note

Dissolve in water to a concentration of 5 mg/mL.

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
0000516088
0000454811
0000454811
0000516088
0000288315

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Consulter la Bibliothèque de documents

Xiaolong Tang et al.
Nature communications, 8(1), 318-318 (2017-08-23)
Distant metastasis is the main cause of breast cancer-related death; however, effective therapeutic strategies targeting metastasis are still scarce. This is largely attributable to the spatiotemporal intratumor heterogeneity during metastasis. Here we show that protein deacetylase SIRT7 is significantly downregulated
Can Yang et al.
Developmental and comparative immunology, 100, 103426-103426 (2019-07-02)
Interferon regulated factor 5 (IRF5) is a key regulator of inflammatory responses in human and mammals; however, its role in teleost remains largely unknown. In this study, IRF5 homologue of black carp (Mylopharyngodon piceus) has been cloned and characterized, which
Sheng-Na Li et al.
Journal of medical virology, 91(9), 1668-1678 (2019-05-21)
Retinoic acid-inducible gene-I (RIG-I) belongs to the RIGI-like receptors (RLRs), a class of primary pattern recognition receptors. It senses viral double-strand RNA in the cytoplasm and delivers the activated signal to its adaptor virus-induced signaling adapter (VISA), which then recruits
Sayuri Ueda et al.
Cellular signalling, 62, 109344-109344 (2019-06-16)
Target of rapamycin complex 1 (TORC1) protein kinase responds to various stresses including genotoxic stress. However, its molecular mechanism is poorly understood. Here, we show that DNA damage induces nonselective and selective autophagy in budding yeast. DNA damage caused the
Ping Kang et al.
Scientific reports, 7(1), 16369-16369 (2017-11-29)
Transcriptional coordination is a vital process contributing to metabolic homeostasis. As one of the key nodes in the metabolic network, the forkhead transcription factor FOXO has been shown to interact with diverse transcription co-factors and integrate signals from multiple pathways
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