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Merck

L4170

LDN-57444

≥98% (HPLC)

Synonyme(s) :

3-(O-acetyloxime), 5-chloro-1-[(2,5-dichlorophenyl)methyl]-1H-Indole-2,3-dione, C30, LDN 57444

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About This Item

Formule empirique (notation de Hill) :
C17H11Cl3N2O3
Numéro CAS:
668467-91-2
Poids moléculaire :
397.64
NACRES:
NA.77
PubChem Substance ID:
329817408
UNSPSC Code:
12352200
MDL number:
MFCD09037562

Nom du produit

LDN-57444, ≥98% (HPLC)

InChI

1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-

SMILES string

CC(=O)O\N=C1/C(=O)N(Cc2cc(Cl)ccc2Cl)c3ccc(Cl)cc13

InChI key

OPQRFPHLZZPCCH-PGMHBOJBSA-N

assay

≥98% (HPLC)

form

solid

storage condition

desiccated
protect from light

solubility

DMSO: 16 mg/mL

storage temp.

2-8°C

Quality Level

100

Catégories apparentées

Biochem/physiol Actions

LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
0000463004
0000463003
0000463003
0000463004
0000345065

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Thomas Vogl et al.
Nature communications, 9(1), 3589-3589 (2018-09-06)
Numerous synthetic biology endeavors require well-tuned co-expression of functional components for success. Classically, monodirectional promoters (MDPs) have been used for such applications, but MDPs are limited in terms of multi-gene co-expression capabilities. Consequently, there is a pressing need for new
Chih-Wei Kao et al.
Plant molecular biology, 92(6), 643-659 (2016-11-01)
The beneficial root-colonizing fungus Piriformospora indica stimulates root development of Chinese cabbage (Brassica campestris subsp. Chinensis) and this is accompanied by the up-regulation of a τ-class glutathione (GSH)-S-transferase gene (BcGSTU) (Lee et al. 2011) in the roots. BcGSTU expression is
K Beernaert et al.
European journal of cancer care, 25(4), 534-543 (2016-06-09)
Despite the growing consensus on the benefits of initiating palliative care early in the disease trajectory, it remains unclear at what point palliative care needs emerge. This study investigates quality of life and unmet palliative care needs at three phases
Giulia Chitarrini et al.
Protoplasma, 254(6), 2095-2106 (2017-03-23)
Metabolic changes can occur in plants in response to abiotic stress. Extensive use of leaf discs (mechanical wounding) in studies regarding the effect on the biochemical response of the grapevine to different types of biotic stress makes it necessary to
Amanda J Steiman et al.
The Journal of rheumatology, 41(9), 1808-1816 (2014-08-03)
Systemic lupus erythematosus (SLE) is typically a relapsing/remitting disease. However, some patients experience prolonged remission. These patients may provide further insights into SLE pathophysiology. In this study we characterize their clinical course. Prolonged remission was defined as Systemic Lupus Erythematosus
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