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Merck

L5900

Linoleic Acid-Water Soluble

powder, BioReagent, suitable for cell culture

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A propos de cet article

NACRES:
NA.75
UNSPSC Code:
12352211
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biological source

plant (Safflower oil)

product line

BioReagent

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 50 mg/mL

storage temp.

−20°C

Quality Level

Application

Linoleic acid-water soluble has been used as a component of fatting media for the in vitro steatosis induction of primary human hepatocytes (PHH).

Biochem/physiol Actions

Linoleic acid (LA) is an arachidonic acid precursor, which is present in vegetable oils. It enhances wound healing in diabetic rats. LA triggers tumor and apoptosis in colorectal cancer cells. The levels of LA in adipose tissue and platelets are associated with coronary artery disease. Linoleic acid binds to molecules, such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.

Other Notes

Contains approx. 30 mg of linoleic acid per gram; balance methyl-β-cyclodextrin.
Package size based on linoleic acid content.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Consulter la Bibliothèque de documents

Chemical-defined and albumin-free generation of human atrial and ventricular myocytes from human pluripotent stem cells
Pei F, et al.
Stem Cell Research, 19, 94-103 (2017)
Enhancement effects of BSA and linoleic acid on hybridoma cell growth and antibody production
Cell Culture Engineering IV, 51-56 (1994)
María Alejandra Moreno et al.
Journal of ethnopharmacology, 216, 283-294 (2018-01-09)
The Argentinean medicinal plant Tetraglochin andina Ciald, formerly classified as T. cristatum (Britton) Rothm is used in traditional medicine by inhabitants from Argentinean northwestern highlands (Puna) to treat candidiasis and as anti-inflammatory. To assess the potential of the crude drug
Takashi Okumura et al.
Oncotarget, 8(11), 18280-18295 (2017-04-15)
Pancreatic cancer progression involves components of the tumor microenvironment, including stellate cells, immune cells, endothelial cells, and the extracellular matrix. Although peripancreatic fat is the main stromal component involved in extra-pancreatic invasion, its roles in local invasion and metastasis of
B R Abdel-Halim
Theriogenology, 114, 143-148 (2018-04-07)
The current study was conducted to investigate the effect of linoleic acid-treated oocytes during in vitro maturation (IVM) on cumulus cell expansion, oocyte nuclear maturation, blastocyst development and DNA damage of cumulus cells and how its effects were alleviated by supplementation

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