M2435
c-Myc Peptide
≥97%, lyophilized powder
Synonyme(s) :
c-Myc tag
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Laissez-nous vous aiderNom du produit
c-Myc Peptide, lyophilized powder
biological source
synthetic
assay
≥97%
form
lyophilized powder
mol wt
1203.3 Da
concentration
5-10 μg/mL (Suggested working concentration to compete out the binding of c-Myc)
technique(s)
protein extraction: suitable
storage temp.
−20°C
Quality Level
Application
Useful for displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific.
General description
The c-Myc Peptide is a synthetic peptide with an amino acid sequence that corresponds to the amino acids 410-419 of the C-terminal of human c-myc.
Other Notes
Amino acid sequence is corresponds to amino acids 410-419 of the C-terminal of human c-Myc.
Lyophilized from 0.1% TFA in H2O
Preparation Note
Dissolve in water to a final concentration of 5 mg/mL.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Yanxiao Zhang et al.
Oncotarget, 8(4), 5761-5773 (2016-12-23)
PAX8-PPARG fusion protein (PPFP) results from a t(2;3)(q13;p25) chromosomal translocation, is found in 30% of follicular thyroid carcinomas, and demonstrates oncogenic capacity in transgenic mice. A PPARG ligand, pioglitazone, is highly therapeutic in mice with PPFP thyroid cancer. However, only
Daria D Korotkova et al.
Cell reports, 29(4), 1027-1040 (2019-10-24)
The molecular basis of higher regenerative capacity of cold-blooded animals comparing to warm-blooded ones is poorly understood. Although this difference in regenerative capacities is commonly thought to be a result of restructuring of the same regulatory gene network, we hypothesized
Atanas G Atanasov et al.
Biochimica et biophysica acta, 1783(8), 1536-1543 (2008-04-03)
Hexose-6-phosphate dehydrogenase (H6PDH) has been shown to stimulate 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-dependent local regeneration of active glucocorticoids. Here, we show that coexpression with H6PDH results in a dramatic shift from 11beta-HSD1 oxidase to reductase activity without affecting the activity
Lian-Mei Tan et al.
The EMBO journal, 37(19) (2018-08-15)
In eukaryotes, heterochromatin regions are typically subjected to transcriptional silencing. DNA methylation has an important role in such silencing and has been studied extensively. However, little is known about how methylated heterochromatin regions are subjected to silencing. We conducted a
Advait Subramanian et al.
Cell, 176(6), 1461-1476 (2019-03-09)
Maintaining the optimal performance of cell processes and organelles is the task of auto-regulatory systems. Here we describe an auto-regulatory device that helps to maintain homeostasis of the endoplasmic reticulum (ER) by adjusting the secretory flux to the cargo load.
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