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Merck

M5162

MOPS

BioXtra, ≥99.5% (titration)

Synonyme(s) :

Acide 3-(N-morpholino)propanesulfonique, Acide 4-morpholinopropanesulfonique

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A propos de cet article

Formule empirique (notation de Hill) :
C7H15NO4S
Numéro CAS:
Poids moléculaire :
209.26
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
214-478-5
Beilstein/REAXYS Number:
1106776
MDL number:
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InChI key

DVLFYONBTKHTER-UHFFFAOYSA-N

InChI

1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

SMILES string

OS(=O)(=O)CCCN1CCOCC1

grade

reagent grade

sterility

non-sterile

product line

BioXtra

assay

≥99.5% (titration)

form

powder

technique(s)

cell culture | mammalian: suitable, electrophoresis: suitable

impurities

Insoluble matter, passes filter test

ign. residue (900°C)

≤0.1% (as SO4)

loss

≤1% loss on drying, 110°C

pH

2.5-4.0 (1 M in H2O)

useful pH range

6.5-7.9

pKa (25 °C)

7.2

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%, sulfate (SO42-): ≤0.005%

cation traces

Al: ≤0.0005%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.001%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Li: ≤0.0005%, Mg: ≤0.0005%, Mn: ≤0.0005%, Mo: ≤0.0005%, Na: ≤0.005%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.0005%, Zn: ≤0.0005%

absorption

≤0.015 at 280 in H2O at 1 M, ≤0.020 at 260 in H2O at 1 M

λ

1 M in H2O

suitability

suitable for electrophoresis

Quality Level

application(s)

diagnostic assay manufacturing

storage temp.

room temp

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General description

MOPS is a morpholino propanesulfonic acid, a structural analog to MES, the ethanesulfonic acid (first introduced by Good et al.), developed to meet the following criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pK a with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range and reasonably easily synthesized.

Application


  • Micro-osteoperforations accelerate orthodontic tooth movement by stimulating periodontal ligament cell cycles : cette étude explore l'utilisation du tampon MOPS dans un cadre orthodontique pour favoriser l'accélération du déplacement dentaire, en améliorant l'efficacité des traitements et les résultats des patients (Sugimori et al., 2018).

  • Chitosan-Promoted Direct Electrochemistry of Human Sulfite Oxidase : la recherche démontre le rôle clé des tampons MOPS dans le maintien de la stabilité et de l'activité enzymatiques lors des études électrochimiques, ce qui offre des perspectives pour des applications biochimiques avancées (Kalimuthu et al., 2017).

  • Peptide fractionation by SDS-free polyacrylamide gel electrophoresis for proteomic analysis via DF-PAGE : l'étude utilise le tampon MOPS dans des techniques électrophorétiques innovantes, pour améliorer la résolution et la séparation des peptides, ce qui facilite ainsi les analyses protéomiques (Ramos et al., 2012).

Features and Benefits

Features:
  1. Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
  2. Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
  3. M-Clarity Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity Program
  4. Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
  5. Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
  6. Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
    1. Site quality assessment
    2. ISO 9001 certificate
    3. Detailed product specifications
    4. Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)
Benefits:
  1. Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
  2. Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
  3. Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
  4. Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
  5. Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
  6. Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.

Other Notes

Comparez facilement les spécifications des différents produits à base de MOPS grâce au Tableau de spécification du MOPS.

Legal Information

M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Consulter la Bibliothèque de documents

Y S L Lee et al.
Human reproduction (Oxford, England), 30(3), 543-552 (2015-01-09)
What is the relationship between cleavage stage embryo kinetics, blastocyst metabolism and subsequent embryo viability? Embryos cleaving faster at the first cleavage division resulted in blastocysts with a larger inner cell mass (ICM), higher glucose consumption, lower glycolytic rate, higher
Junji Suzuki et al.
Nature communications, 5, 4153-4153 (2014-06-14)
The endoplasmic reticulum (ER) and mitochondria accumulate Ca(2+) within their lumens to regulate numerous cell functions. However, determining the dynamics of intraorganellar Ca(2+) has proven to be difficult. Here we describe a family of genetically encoded Ca(2+) indicators, named calcium-measuring
Sanna Byström et al.
Journal of proteome research, 13(11), 4607-4619 (2014-09-19)
The brain is a vital organ and because it is well shielded from the outside environment, possibilities for noninvasive analysis are often limited. Instead, fluids taken from the spinal cord or circulatory system are preferred sources for the discovery of
Alexandre Albanese et al.
ACS nano, 8(6), 5515-5526 (2014-05-07)
A nanoparticle's physical and chemical properties at the time of cell contact will determine the ensuing cellular response. Aggregation and the formation of a protein corona in the extracellular environment will alter nanoparticle size, shape, and surface properties, giving it
Lovisa Lundholm et al.
International journal of radiation biology, 90(8), 718-726 (2014-03-22)
We aimed to analyze the activation status of commonly deregulated receptor tyrosine kinases (RTK) in human non-small cell lung cancer (NSCLC) tumor initiating cells (TIC) previously demonstrated to be refractory to ionizing radiation and chemotherapy. Phosphorylated RTK and important signaling

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