M5284
IgG1 Isotype Control from murine myeloma
clone MOPC 21, purified immunoglobulin, buffered aqueous solution
Synonyme(s) :
Isotype control antibody
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Nom du produit
IgG1 Isotype Control from murine myeloma, clone MOPC 21, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
clone
MOPC 21, monoclonal
form
buffered aqueous solution
technique(s)
flow cytometry: suitable
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
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Application
IgG1 Isotype Control from murine myeloma has been used in:
extracellular DNA fluorescence assay
extracellular DNA fluorescence assay
- reactive oxygen species (ROS) production analysis
- immunohistochemistry
- double labelling immunohistochemistry
- immunofluorescence
- flow cytometry
- immunoprecipitation
IgG1 isotype control antibodies are suitable for use in immunohistochemistry (7μg/ml) and immunoblotting. The product may also be used for flow cytometry.
Biochem/physiol Actions
IgG1 isotype control antibody is specific for anti-mouse whole serum and anti-mouse IgG1. The product does not react with antisera to mouse IgA, IgM, IgG2a, IgG2b, and IgG3.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice . I
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. It mainly helps in immune defense. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide
Classe de stockage
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Lingyun Chen et al.
Journal of agricultural and food chemistry, 54(15), 5577-5582 (2006-07-20)
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Megan S Inkeles et al.
JCI insight, 1(15), e88843-e88843 (2016-10-05)
Transcriptome profiles derived from the site of human disease have led to the identification of genes that contribute to pathogenesis, yet the complex mixture of cell types in these lesions has been an obstacle for defining specific mechanisms. Leprosy provides
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Gillenius E and Urban CF
Microbes and Infection, 17(5), 327-336 (2015)
High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents
Ma J, et al.
American Journal of Physiology. Heart and Circulatory Physiology, 301(5), H2006-H2017 (2011)
Contenu apparenté
Datasheet
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