M7894
IgG1, Kappa from murine myeloma
clone MOPC 21, ascites fluid, lyophilized powder
Synonyme(s) :
Mouse IgG1-κ
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A propos de cet article
Conjugate:
unconjugated
Clone:
MOPC 21, monoclonal
Application:
Citations:
39
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Laissez-nous vous aiderNom du produit
IgG1, Kappa from murine myeloma, clone MOPC 21, ascites fluid, lyophilized powder
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
clone
MOPC 21, monoclonal
form
lyophilized powder
application(s)
research pathology
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
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Application
IgG1, Kappa from murine myeloma has been used:
- in stimulation assay and enzyme-linked immunosorbent assay (ELISA)
- as isotype controls in islet hormone production
- in flow cytometric analysis, in cell migration assay
- as control antibody in evaluation of methylation
Biochem/physiol Actions
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
The MOPC-21 tumor line that produces mouse IgG1, κ is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Immunoglobulins G are made up of two identical light chains and two identical heavy chains, that are covalently connected by interchain disulphide bonds. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b, IgG2c and IgG3.
Preparation Note
Reconstitute with 1 mL deionized water.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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A Sharland et al.
Transplantation, 65(10), 1370-1377 (1998-06-13)
Liver transplants in the rat strain combination PVG-to-Dark Agouti are spontaneously tolerated, whereas kidney transplants in the same strain combination are rejected in 7-9 days. To identify organ-specific differences that might yield further information about the mechanism of tolerance induction
The Laboratory Rat (2015)
Eva Obermueller et al.
Cancer research, 64(21), 7801-7812 (2004-11-03)
Tumor growth and progression are critically controlled by alterations in the microenvironment often caused by an aberrant expression of growth factors and receptors. We demonstrated previously that tumor progression in patients and in the experimental HaCaT tumor model for skin
J Zhu et al.
American journal of respiratory and critical care medicine, 164(12), 2220-2228 (2001-12-26)
We wished to determine if the inflammatory cells surrounding the airway mucus-secreting glands in chronic bronchitis (CB) were associated with interleukin (IL)-4 and IL-5 mRNA expression and whether the CD8 T cell population expressed these cytokines. Digoxigenin-labeled IL-4 and IL-5
IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines
Lederle W, et al.
International Journal of Cancer. Journal International Du Cancer, 128(12), 2803-2814 (2011)
Contenu apparenté
Datasheet
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