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Merck

N5413

Anti-Nestin antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-FJ21841, Anti-NES, Anti-Nbla00170

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A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD03455626

Principaux documents

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Nom du produit

Anti-Nestin antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~110 kDa (cleaved)
antigen ~177 kDa
antigen ~270 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

technique(s)

flow cytometry: 1:200-1:500
immunohistochemistry: 1:100-1:200
western blot: 1:500-1:1,000

UniProt accession no.

P48681

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

200

Gene Information

human ... NES(10763)
mouse ... Nes(18008)
rat ... Nes(25491)

Catégories apparentées

Biochem/physiol Actions

Nestin (NES) functions as a regulator of proteins which are involved in cell growth. It also interacts with other proteins of the intermediate filament. NES has been studied as a marker of neural stem cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Nestin (NES) is a class VI cytoplasmic protein. It is expressed in the intermediate filaments and has a molecular weight of 177kDa. The gene encoding it is localized on human chromosome 1q23.1 with four exons.

Immunogen

synthetic peptide corresponding to residues 254-270 of human Nestin. This sequence is 93% identical in rat.

Physical form

solution in phosphate buffered saline, containing 0.02% sodium azide.

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Classe de stockage

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificats d'analyse (COA)

Lot/Batch Number
SLCM8908
SLCK2368
SLCG0413
SLCC3419
SLBX5698

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Chhagan Bihari et al.
Hepatology (Baltimore, Md.), 64(4), 1273-1288 (2016-08-04)
Bone marrow (BM) is a reservoir for immune and hematopoietic cells and critical for tissue repair and regeneration. All of these functions are severely altered in cirrhosis. We investigated the cellular and functional state of BM in cirrhosis patients. We
Nianping Zhang et al.
International journal of molecular medicine, 40(3), 814-824 (2017-07-18)
Pluripotent stem cells (PSCs) are regarded as potential sources that provide specific neural cells for cell therapy in some nervous system diseases. However, the mechanisms underlying the neural differentiation of PSCs remain largely unknown. MicroRNAs (miRNAs or miRs) are a class of
Y Chen et al.
Osteoarthritis and cartilage, 23(10), 1728-1735 (2015-06-02)
Osteoarthritis (OA) is a progressive joint disorder. To date, there is not effective medical therapy. Joint distraction has given us hope for slowing down the OA progression. In this study, we investigated the benefits of joint distraction in OA rat
Mohamed Ahmed Eladl et al.
International journal of nephrology and renovascular disease, 10, 61-76 (2017-03-07)
Several renal disorders affect the glomerular podocytes. Compensatory structural and functional changes have been observed in animals that have undergone unilateral renal ablation. These changes occur as a pliant response to quench the increased functional demand to maintain homeostasis of
Wei Zhao et al.
Scientific reports, 6, 21176-21176 (2016-02-18)
Restenosis or occlusion after vascular procedures is ascribed to intimal hyperplasia. Transforming growth factor (TGF)-β1 is involved in recruitment of mesenchymal stem cells (MSCs) following arterial injury, and its release from latent TGF-binding protein by matrix metalloproteinase (MMP)-14-induced proteolysis contributes
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Contenu apparenté

Data Sheet - N5413

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