O5250
D-Ornithine monohydrochloride
~98%
Synonyme(s) :
(R)-2,5-Diaminopentanoic acid monohydrochloride
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A propos de cet article
Formule empirique (notation de Hill) :
C5H12N2O2 · HCl
Numéro CAS:
Poids moléculaire :
168.62
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
240-729-3
MDL number:
Beilstein/REAXYS Number:
4153339
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Laissez-nous vous aiderNom du produit
D-Ornithine monohydrochloride, ~98%
InChI key
GGTYBZJRPHEQDG-PGMHMLKASA-N
InChI
1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m1./s1
SMILES string
Cl[H].NCCC[C@@H](N)C(O)=O
assay
~98%
form
powder
color
white
mp
239 °C
Quality Level
Biochem/physiol Actions
D-Ornithine cleave proteins at cysteine residues.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Susan E Cellitti et al.
Nature chemical biology, 7(8), 528-530 (2011-04-29)
D-ornithine has previously been suggested to enhance the expression of pyrrolysine-containing proteins. We unexpectedly discovered that uptake of D-ornithine results in the insertion of a new amino acid, pyrroline-carboxy-lysine (Pcl) instead of the anticipated pyrrolysine (Pyl). Our feeding and biochemical
Nicole Berthold et al.
Antimicrobial agents and chemotherapy, 57(1), 402-409 (2012-11-02)
Proline-rich antimicrobial peptides (PrAMPs) from insects and mammals have recently been evaluated for their pharmaceutical potential in treating systemic bacterial infections. Besides the native peptides, several shortened, modified, or even artificial sequences were highly effective in different murine infection models.
Isabel Araque et al.
Food microbiology, 33(1), 107-113 (2012-11-06)
The accumulation of citrulline and ornithine in wine or beer as a result of the arginine catabolism of some lactic acid bacteria (LAB) species increases the risk of ethyl carbamate and putrescine formation, respectively. Several LAB species, which are found
Manami Oya et al.
The Journal of biological chemistry, 288(7), 4513-4521 (2012-12-28)
Although amino acids are dietary nutrients that evoke the secretion of glucagon-like peptide 1 (GLP-1) from intestinal L cells, the precise molecular mechanism(s) by which amino acids regulate GLP-1 secretion from intestinal L cells remains unknown. Here, we show that
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming
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