P5891
L-Pyroglutamic acid 2-naphthylamide
≥99% (TLC), suitable for ligand binding assays
Synonyme(s) :
L-Pyroglutamic acid β-naphthylamide, L-Pyrrolidonyl-β-naphthylamide, N1-(2-Naphthyl)-L-pyroglutamic acid, PYR
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A propos de cet article
Formule empirique (notation de Hill) :
C15H14N2O2
Numéro CAS:
Poids moléculaire :
254.28
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
244-809-9
MDL number:
Beilstein/REAXYS Number:
5066652
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Laissez-nous vous aiderNom du produit
L-Pyroglutamic acid 2-naphthylamide, ≥99% (TLC)
Quality Level
assay
≥99% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
2-8°C
SMILES string
O=C1CC[C@H](N1)C(=O)Nc2ccc3ccccc3c2
InChI
1S/C15H14N2O2/c18-14-8-7-13(17-14)15(19)16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2,(H,16,19)(H,17,18)/t13-/m0/s1
InChI key
BZEPQNMASTUAMY-ZDUSSCGKSA-N
Application
A substrate for pyroglutamate aminopeptidase. Used for differentiation of Group A streptococci and enterococci from other streptococci.
Biochem/physiol Actions
Pyroglutamic acid is known to participate in the gamma-glutamyl cycle. Recent studies show that a congenital metabolic error was associated with increased pyroglutamic excretion in urine.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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Jean-Sébastien Jouhanneau et al.
Nature communications, 9(1), 1540-1540 (2018-04-20)
A defining feature of cortical layer 2/3 excitatory neurons is their sparse activity, often firing in singlets of action potentials. Local inhibitory neurons are thought to play a major role in regulating sparseness, but which cell types are recruited by
S Santisi et al.
Journal of applied microbiology, 127(3), 618-629 (2019-03-09)
The aims of this study were: (i) the characterization of the structure of the indigenous microbial community associated with the sediments under study; (ii) the isolation and characterization of microbial consortia able to degrade the aged hydrocarbons contaminating the sediments
Alaa Alachkar et al.
Frontiers in pharmacology, 8, 709-709 (2017-10-28)
The involvement of histamine H3 receptors (H3Rs) in memory is well known, and the potential of H3R antagonists in therapeutic management of neuropsychiatric diseases, e.g., Alzheimer disease (AD) is well established. Therefore, the effects of histamine H3 receptor (H3R) antagonist