P7002
Phospho(enol)pyruvic acid trisodium salt hydrate
≥97% (enzymatic), powder
Synonyme(s) :
2-(Phosphonooxy)-2-propenoic acid trisodium salt, PEP
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A propos de cet article
Formule linéaire :
C3H2O6PNa3 · x H2O
Numéro CAS:
Poids moléculaire :
233.99 (anhydrous basis)
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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Phospho(enol)pyruvic acid trisodium salt hydrate, ≥97% (enzymatic)
Quality Level
assay
≥97% (enzymatic)
form
powder
solubility
water: 100 mg/mL, clear to slightly hazy, colorless to very faintly yellow
storage temp.
−20°C
SMILES string
[Na].OC(=O)C(=C)OP(O)(O)=O
InChI
1S/C3H5O6P.Na.H/c1-2(3(4)5)9-10(6,7)8;;/h1H2,(H,4,5)(H2,6,7,8);;
InChI key
KZPUEZVJSLLABH-UHFFFAOYSA-N
Application
Phospho(enol)pyruvic acid trisodium salt hydrate has been used in:
- several enzyme activity assays, such as PRPP synthetase (PRPPS) assay, ribokinase (RK) assay, adenine phosphoribosyltransferase (APRT) assay
- in the reaction mixture for enzyme kinetic assay to determine platelet-derived growth factor receptor α (PDGFRA) kinetic parameters
- as a component in buffer B to react with adenosine diphosphate (ADP) to form adenosine triphosphate (ATP) for energy charge measurement
Biochem/physiol Actions
Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogenesis. In glycolysis, PEP is metabolized by pyruvate kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.
Phosphoenolpyruvic acid plays a major role in the initial step of glycolysis by acting as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Kento Tokuyama et al.
Biotechnology and bioengineering, 115(6), 1542-1551 (2018-02-20)
Gene deletion strategies using flux balance analysis (FBA) have improved the growth-coupled production of various compounds. However, the productivities were often below the expectation because the cells failed to adapt to these genetic perturbations. Here, we demonstrate the productivity of
Structural and biochemical studies of the PDGFRA kinase domain
Liang L, et al.
Biochemical and Biophysical Research Communications, 477(4), 667-672 (2016)
Casimir Ledoux Sofeu et al.
PLoS neglected tropical diseases, 12(9), e0006597-e0006597 (2018-09-07)
Canine rabies is endemic in Cameroon, but human rabies exposures and cases are likely underreported because of inadequate surveillance. In 2014, the surveillance network in the West region of Cameroon was reinforced by introducing a new anti-rabies center, a framework