Accéder au contenu
Merck

S0266

Spermidine

BioReagent, Molecular Biology, suitable for cell culture, ≥98%

Synonyme(s) :

1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane

Se connecter pour consulter les tarifs organisationnels et contractuels.

Sélectionner une taille de conditionnement

A propos de cet article

Formule linéaire :
NH2(CH2)3NH(CH2)4NH2
Numéro CAS:
124-20-9
Poids moléculaire :
145.25
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
24899434
EC Number:
204-689-0
Beilstein/REAXYS Number:
1698591
MDL number:
MFCD00008229

Principaux documents

Voir toute la documentation
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider

Nom du produit

Spermidine, BioReagent, Molecular Biology, suitable for cell culture, ≥98%

InChI key

ATHGHQPFGPMSJY-UHFFFAOYSA-N

InChI

1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2

SMILES string

NCCCCNCCCN

grade

Molecular Biology

product line

BioReagent

assay

≥98%

form

solid or liquid

mol wt

145.25 (AMU)

technique(s)

cell culture | mammalian: suitable

refractive index

n20/D 1.479 (lit.)

density

0.925 g/mL at 25 °C (lit.)

foreign activity

DNase, RNase, and protease, none detected

storage temp.

room temp

Quality Level

200

Gene Information

rat ... Ppm1a(24666)

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Application

Spermidine has been used in the preparation of gold beads and as a component in nuclei isolation buffer (NIB).
Spermidine is suitable for use in molecular biology buffers and for precipitation of DNA >100 bp in length. It was used to deliver DNA in plants and mammalian cells by particle bombardment technique.

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Spermidine helps to maintain the proper activity of gene expression. This polyamine plays a key role in intermediate metabolism. It also serves as an inhibitor of the acetyl transferase activity of E1A-associated protein p300 (EP300). Spermidine participates in cell growth.

Disclaimer

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

General description

Spermidine belongs to the natural polyamines, that are found in chloroplasts and in bacterial or eukaryotic cells.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Classe de stockage

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

233.6 °F - closed cup

flash_point_c

112 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCN7480
BCCP1081
BCCP1080
BCCP0622
BCCN9920

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Rechercher un(e) COA

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Is this a spermidine solution or a neat liquid, and what is the concentration?

    Based on a density of 0.925 g/mL and a molecular weight of 145.25, this neat liquid has an effective molarity of 6.4 M.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Elumalai Sivamani et al.
Plant cell reports, 28(2), 213-221 (2008-11-19)
We have developed a method by which remarkably higher efficiencies of transient and stable transformation were achieved in bombardment transformation of plants. Over fivefold increase in transient gus gene expression was achieved when rice or maize suspension cells were bombarded
Spermidine delays aging in humans
Madeo F, et al.
Aging (Albany. NY.), 10(8), 2209-2209 (2018)
Molecular Determinants of Metaplastic and Neoplastic Transformation in the Esophageal Epithelium
Progress in Molecular Biology and Translational Science, 96, 63-92 (2010)
Delivery of DNA to skin by particle bombardment.
Shixia Wang et al.
Methods in molecular biology (Clifton, N.J.), 245, 185-196 (2004-01-07)
Organization, developmental dynamics, and evolution of plastid nucleoids
Sato N, et al.
International Review of Cytology, 232, 217-262 (2003)
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique