S0615

FBS Superior

Name: FBS Superior
Brand: SIGMA

Supplemented FBS, EU approved

Synonyme(s) :

FBS, FCS, Fetal Bovine Sera, Fetal Bovine Serum, Supplemented FCS

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About This Item

NACRES:

NA.71

UNSPSC Code:

12352207

biological source:

bovine fetus

origin:

non-USA origin

sterility:

sterile-filtered

shipped in:

dry ice

Nom du produit

FBS Superior, Supplemented FBS, EU approved

biological source

bovine fetus

sterility

sterile-filtered

product line

FBS Select

quality

EU approved

composition

hemoglobin, <50 mg/dL

origin

non-USA origin

impurities

≤25 EU/mL endotoxin

shipped in

dry ice

storage temp.

−20°C

Quality Level

400

Application

FBS Superior has been used:

as a component of differentiation medium, growth medium, induction medium, and Dulbecco′s modified Eagle medium (DMEM) for murine thermogenic adipocytes culture
as a component of the culture medium along with DMEM high glucose (HG) for cell viability check
as a component of minimum essential medium Eagle (MEM) to cultivate Caco-2 human colon adenocarcinoma cells

Biochem/physiol Actions

Fetal bovine serum(FBS) Superior is a South American source of FBS supplemented with various growth-promoting compounds to allow for a more consistent product. This supplementation can reduce or eliminate the need to test multiple batches on specific cell lines. FBS Superior can be used just like regular FBS, delivers nutrients, growth, and attachment factors, and protects cells from oxidative damage and apoptosis by mechanisms that are difficult to reproduce in serum-free media (SFM) systems.

Fetal bovine serum (FBS) comprises growth factors (GFs) and other elements that are required for the expansion, maintenance, attachment, and proliferation of adipose-derived stromal cells (ASC) in vitro.

General description

Fetal bovine serum (FBS), a traditional serum supplement, is used in animal cell culture media. It is obtained from the fetus of the cow.

Classe de stockage

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Fabrication and Characterization of Glycerol/Chitosan/Polyvinyl Alcohol-Based Transparent Hydrogel Films Loaded with Silver Nanoparticles for Antibacterial Wound Dressing Applications.

Ali Samadi et al.

Advanced biomedical research, 10, 4-4 (2021-05-08)

Wounds have a bad prognostic nature and excessive discharges whose regular wound dressings are ineffective. Hydrogels are the best candidates for dressing such wounds due to their high water content and ability to exchange substances. Accordingly, the purpose of this

The use of fetal bovine serum: ethical or scientific problem?

Carlo E A Jochems et al.

Alternatives to laboratory animals : ATLA, 30(2), 219-227 (2002-04-25)

Fetal bovine serum (FBS) is a common component of animal cell culture media. It is harvested from bovine fetuses taken from pregnant cows during slaughter. FBS is commonly harvested by means of a cardiac puncture without any form of anaesthesia.

Making the Switch: Alternatives to Fetal Bovine Serum for Adipose-Derived Stromal Cell Expansion.

Carla Dessels et al.

Frontiers in cell and developmental biology, 4, 115-115 (2016-11-02)

Adipose-derived stromal cells (ASCs) are being used extensively in clinical trials. These trials require that ASCs are prepared using good manufacturing practices (GMPs) and are safe for use in humans. The majority of clinical trials in which ASCs are expanded

Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake.

Arjen J Jakobi et al.

Nature communications, 11(1), 440-440 (2020-01-25)

p62/SQSTM1 is an autophagy receptor and signaling adaptor with an N-terminal PB1 domain that forms the scaffold of phase-separated p62 bodies in the cell. The molecular determinants that govern PB1 domain filament formation in vitro remain to be determined and

Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2).

Julia Huetter et al.

Cancer immunology research, 8(7), 895-911 (2020-04-22)

The immunoglobulin-like domain containing receptor 2 (ILDR2), a type I transmembrane protein belonging to the B7 family of immunomodulatory receptors, has been described to induce an immunosuppressive effect on T-cell responses. Besides its expression in several nonlymphoid tissue types, we

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