S5394
Lipoprotein Deficient Serum from fetal calf
frozen liquid
Synonyme(s) :
Fetal Calf Serum, Lipoprotein Deficient Serum
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A propos de cet article
NACRES:
NA.61
UNSPSC Code:
12352207
Biological source:
bovine fetus
Form:
frozen liquid
Shipped in:
dry ice
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Laissez-nous vous aiderbiological source
bovine fetus
form
frozen liquid
concentration
≥14 mg protein/mL Biuret
Quality Level
impurities
<1 ng/mg protein endotoxin, <5 % of normal lipoprotein
shipped in
dry ice
storage temp.
−20°C
General description
Studies show that the production of sterols is reduced in human fibroblasts cultured in the presence of lipoprotein deficient serum.
Application
Lipoprotein Deficient Serum from fetal calf has been used as a supplement in culture media to grow Chinese hamster ovary (CHO)-derived cells, thymic lobes and human peripheral blood mononuclear cells (PBMCs).
Preparation Note
Dialyzed against Dulbecco′s phosphate buffered saline, pH 7.4-7.5
0.2 μm filtered
Classe de stockage
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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Lipid-mediated presentation of MHC class II molecules guides thymocytes to the CD4 lineage
Komaniwa S, et al.
European Journal of Immunology, 39(1), 96-112 (2009)
Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP)
Shao W and Espenshade PJ
The Journal of Biological Chemistry, 289(11), 7547-7557 (2014)
Brian T Emmer et al.
PLoS genetics, 17(1), e1009285-e1009285 (2021-01-30)
Hypercholesterolemia is a causal and modifiable risk factor for atherosclerotic cardiovascular disease. A critical pathway regulating cholesterol homeostasis involves the receptor-mediated endocytosis of low-density lipoproteins into hepatocytes, mediated by the LDL receptor. We applied genome-scale CRISPR screening to query the
P M Giles et al.
Clinica chimica acta; international journal of clinical chemistry, 113(2), 183-191 (1981-06-18)
The biosynthesis and efflux of sterols from cells into the medium were investigated in skin fibroblasts from a control, a patient with obligate heterozygous familial hypercholesterolaemia and a patient with the homozygous condition. The behaviour of the cells was studied
Ying Wang et al.
Cell death discovery, 7(1), 201-201 (2021-08-06)
Coenzyme Q (CoQ) is a lipid-like mobile electron transporter of the mitochondrial respiratory chain. Patients with partial loss-of-function mutations in the CoQ biosynthesis pathway suffer from partial primary CoQ deficiency (MIM 607426). This leads to mitochondrial dysfunction, which presents like
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