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Merck

S5442

SyntheChol® NS0 Supplement

500 ×, synthetic cholesterol, animal component-free, sterile-filtered, aqueous solution, suitable for cell culture

Synonyme(s) :

Cholesterol solution

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About This Item

Formule empirique (notation de Hill) :
C27H46O
Numéro CAS:
Poids moléculaire :
386.65
UNSPSC Code:
12352211
eCl@ss:
39023139
PubChem Substance ID:
NACRES:
NA.75
MDL number:

Nom du produit

SyntheChol® NS0 Supplement, 500 ×, synthetic cholesterol, animal component-free, sterile-filtered, aqueous solution, suitable for cell culture

SMILES string

[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)CCCC(C)C

InChI key

HVYWMOMLDIMFJA-DPAQBDIFSA-N

InChI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

biological source

non-animal source

sterility

sterile-filtered

product line

BioXtra

form

aqueous solution

concentration

500 ×

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

Quality Level

Gene Information

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Application

SyntheChol® NS0 Supplement is used as media supplement for NS0 mouse myeloma cell growth and the growth of other cholesterol-dependent cell lines.

Features and Benefits

Synthetic, non-animal cholesterol solution that is designed as a supplement to our hybridoma media formulations to promote excellent cell growth and protein productivity for NS0 mouse myeloma and other cholesterol-dependent cell lines.

Legal Information

SyntheChol is a registered trademark of Merck KGaA, Darmstadt, Germany

Classe de stockage

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Consulter la Bibliothèque de documents

Arthur Nathan Brodsky et al.
Methods (San Diego, Calif.), 56(3), 408-417 (2011-10-29)
DNA microarray analysis of gene expression has become a valuable tool for bioprocessing research aimed at improving therapeutic protein yields. The highly parallel nature of DNA microarray technology allows researchers to assess hundreds of gene simultaneously, essentially enabling genome-wide snapshots.
Suba Dharshanan et al.
Cytotechnology, 66(4), 625-633 (2013-07-25)
From our recent publications, it was found that the deimmunization method (Dharshanan et al. (2012) Sci Res Essays 7:2288-2299) should be applied for the development of humanized anti-C2 monoclonal antibody (H1C2 mAb). However, the overlapping-PCR mutagenesis procedure used to insert
Steve Schoonooghe et al.
BMC biotechnology, 9, 70-70 (2009-08-13)
Tumour associated antigens on the surface of tumour cells, such as MUC1, are being used as specific antibody targets for immunotherapy of human malignancies. In order to address the poor penetration of full sized monoclonal antibodies in tumours, intermediate sized
Marco Guadagnoli et al.
Blood, 117(25), 6856-6865 (2011-05-06)
APRIL (A proliferation-inducing ligand) is a TNF family member that binds two TNF receptor family members, TACI and BCMA. It shares these receptors with the closely related TNF family member, B-cell activating factor (BAFF). Contrary to BAFF, APRIL binds heparan
Nancy Lynn Booth et al.
Cancer immunology, immunotherapy : CII, 58(8), 1229-1244 (2008-12-18)
We have developed a high-throughput screen (HTS) to search for novel molecules that can synergize with TRAIL, thus promoting apoptosis of ACHN renal tumor cells in a combinatorial fashion. The HTS detects synthetic compounds and pure natural products that can

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