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Merck

S9399

Staphylococcal enterotoxin A

from Staphylococcus aureus, lyophilized powder, enterotoxin

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A propos de cet article

Numéro CAS:
642595-84-4
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00082015
Quality level:
200

Principaux documents

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Nom du produit

Staphylococcal enterotoxin A from Staphylococcus aureus,

contains

sodium phosphate buffer as balance

composition

Protein, ~10% Lowry

availability

not available in USA

impurities

Staphylococcal enterotoxin B (SEB), essentially free

solubility

H2O: complete 1 mg/ml, clear, colorless

storage temp.

2-8°C

Quality Level

200

Application

Staphylococcal enterotoxin A from Staphylococcal aureus was injected peritoneally in mice to induce sepsis.10
Staphylococcal enterotoxin A from Staphylococcus aureus has been used as an external standard in for the verification of TRANSIA assay kit, RIDASCREEN assay kit and Vidas Set 2 method. For in vitro toxin stimulation of mouse splenocytes.

Biochem/physiol Actions

Staphylococcal enterotoxin A from Staphylococcus aureus is leading agent that causes of food poisoning. A concentration of as little as 0.5 mg/ml is sufficient to result in nausea, vomiting, diarrhea and cramps.8 It stimulates the cell proliferation of peripheral lymphocytes, induces the production of interferons and is important for gut immunity against S. aureus infections.9 It acts as a super antigen for T-lymphocytes.

General description

Staphylococcal enterotoxin A belongs to the family of staphylococcal exotoxins. It is secreted by Staphylococcus aureus, a Gram-positive bacteria.

Packaging

Package size based on protein content

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
0000367998
0000367997
0000367998
0000367997
0000274295

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Consulter la Bibliothèque de documents

Determination of staphylococcal enterotoxins in cheese by immunoenzyme assays
<BIG>Jankovic V, et al.</BIG>
Archives of Biological Sciences, 64, 1449-1454 (2012)
Dong Zhang et al.
Oncoimmunology, 9(1), 1744921-1744921 (2020-04-22)
T cell immunoglobulin and mucin domain-3 (TIM-3) is an immune checkpoint that regulates normal immune responses but can be exploited by tumor cells to evade immune surveillance. TIM-3 is primarily expressed on immune cells, particularly on dysfunctional and exhausted T
Marcin Kłak et al.
Scandinavian journal of infectious diseases, 42(5), 351-358 (2010-01-27)
Haemostatic balance shifts towards pro-coagulation during infection. Plasminogen, a key molecule of fibrinolysis, may play an important role in the pathogenesis of staphylococcal infections. In the present study, we assessed the impact of inhibition of plasminogen activation by tranexamic acid
Hongshi Yu et al.
BMC genomics, 10, 416-416 (2009-09-08)
WNT4 is a critical signalling molecule in embryogenesis and homeostasis, but the elements that control its transcriptional regulation are largely unknown. This study uses comparative cross species sequence and functional analyses between humans and a marsupial (the tammar wallaby,Macropus eugenii)
Staphylococcal enterotoxin A (SEA).
L Spero et al.
Methods in enzymology, 78(Pt A), 331-336 (1981-01-01)
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