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A propos de cet article
Formule empirique (notation de Hill) :
C31H52O3
Numéro CAS:
Poids moléculaire :
472.74
PubChem Substance ID:
eCl@ss:
34058007
UNSPSC Code:
12352205
NACRES:
NA.75
EC Number:
200-405-4
MDL number:
Service technique
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Laissez-nous vous aiderbiological source
plant
Quality Level
description
Synthesized from natural α-tocopherol
product line
BioReagent
form
liquid (or semi-solid)
specific activity
~1360 IU/g
mol wt
Mw 472.74 g/mol
purified by
crystallization
technique(s)
cell culture | insect: suitable
color
white to yellow
solubility
chloroform: soluble 50 mg/mL, clear, colorless to yellow
storage temp.
room temp
SMILES string
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
InChI
1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
InChI key
ZAKOWWREFLAJOT-CEFNRUSXSA-N
General description
α-Tocopherol acetate is a semisynthetic acetate ester of naturally occurring α-tocopherol.
Application
(+)-α-Tocopherol acetate has been used:
- as a supplement in the human embryonic kidney cells (HEK 293) to assess its impact on cell growth
- as a component of Dulbecco′s Modified Eagle Medium/Nutrient Mixture F-12 (DMEM/F12) for immortalized chondrocyte cell line
- as a component of serum-free medium for human colon tissue organ culture
- to test its antioxidant effects on cow articular chondrocytes
Use in insect cell culture applications as an antioxidant.
Biochem/physiol Actions
α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes.
Disclaimer
Since the M.P. is about 25 °C this preparation is usually an oil. Does not air oxidize.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
Classe de stockage
10 - Combustible liquids
wgk
WGK 1
ppe
Eyeshields, Gloves
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Contenu apparenté
Instructions
Optimization of HEK 293 cell growth by addition of non-animal derived components using design of experiments.
Laura Cervera et al.
BMC proceedings, 5 Suppl 8, P126-P126 (2012-03-01)
Michael K Dame et al.
In vitro cellular & developmental biology. Animal, 47(1), 32-38 (2010-11-26)
We have recently shown that a multi-mineral extract from the marine red algae, Lithothamnion calcareum, suppresses colon polyp formation and inflammation in mice. In the present study, we used intact human colon tissue in organ culture to compare responses initiated
Michael K Dame et al.
In vitro cellular & developmental biology. Animal, 46(2), 114-122 (2009-11-17)
Normal and neoplastic human colon tissue obtained at surgery was used to establish conditions for organ culture. Optimal conditions included an atmosphere of 5% CO2 and 95% O2; tissue partially submerged with mucosa at the gas interface; and serum-free medium